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Pharmacokinetic evaluation of radiolabeled intraocular anti‐CLEC14a antibody in preclinical animal species and application in humans

Anti‐angiogenic antibodies are widely used in the treatment of neovascular macular degeneration. Human antibody targeting C‐type lectin domain family 14 member A (CLEC14a) is potential therapeutic agents owing to its antiangiogenic activity. In the present study, we aimed to predict the human intrao...

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Detalles Bibliográficos
Autores principales: Park, Sohyun, Lee, Youn Woo, Oh, Jaeseong, Kim, Su Jin, Lee, Sukmook, Lee, Ho‐Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747121/
https://www.ncbi.nlm.nih.gov/pubmed/36129122
http://dx.doi.org/10.1111/cts.13412