Cargando…

Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of Aidi Injection Treating of Nonsmall Cell Lung Cancer

BACKGROUND: Aidi injection (ADI) is a compound preparation injection of Chinese herbs used to treat patients of nonsmall cell lung cancer (NSCLC) in China. This study aimed to reveal the mechanism of ADI in the treatment of NSCLC by using network pharmacology and molecular docking. METHODS: The rela...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Weizhou, Peng, Wenpan, Li, Yehui, Pan, Tingyu, Feng, Fanchao, Xu, Jie, Zhou, Xianmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747318/ https://www.ncbi.nlm.nih.gov/pubmed/36523419 http://dx.doi.org/10.1155/2022/8350218

Ejemplares similares

Exploring the mechanism of aidi injection for lung cancer by network pharmacology approach and molecular docking validation
por: Zhuang, Zhenjie, et al.
Publicado: (2021)

Material Basis and Mechanism of Chansu Injection for COVID-19 Treatment Based on Network Pharmacology and Molecular Docking Technology
por: Xu, Yong, et al.
Publicado: (2021)

Potential mechanism underlying the effect of matrine on COVID-19 patients revealed through network pharmacological approaches and molecular docking analysis
por: Peng, Wenpan, et al.
Publicado: (2020)

Assessment on the Efficacy and Safety of Aidi Injection Combined with Vinorelbine and Cisplatin for Treatment of Advanced Nonsmall Cell Lung Cancer
por: Zhao, Hua-Ye, et al.
Publicado: (2016)

Meta-Analysis of Aidi Injection and First-Generation Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor Therapy in Treating Advanced Non-Small Cell Lung Cancer
por: Xiao, Na, et al.
Publicado: (2021)

Clinical Efficacy and Safety of Aidi Injection Plus Docetaxel-Based Chemotherapy in Advanced Nonsmall Cell Lung Cancer: A Meta-Analysis of 36 Randomized Controlled Trials
por: Xiao, Zheng, et al.
Publicado: (2018)

Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments
por: Wang, Haojia, et al.
Publicado: (2023)

Exploring the nucleotide molecular mechanism of compound kushen injection for lung adenocarcinoma based on network pharmacology and molecular docking
por: Ye, Zhangpeng, et al.
Publicado: (2022)

The mechanism of triptolide in the treatment of connective tissue disease-related interstitial lung disease based on network pharmacology and molecular docking
por: Zhu, Wen, et al.
Publicado: (2022)

Molecular targets and mechanisms of Guanxinning tablet in treating atherosclerosis: Network pharmacology and molecular docking analysis
por: Niu, Chaofeng, et al.
Publicado: (2023)

Pharmacokinetic herb-drug interactions between Aidi injection and doxorubicin in rats with diethylnitrosamine-induced hepatocellular carcinoma
por: Lu, Yuan, et al.
Publicado: (2021)

Network Pharmacology and Molecular Docking Elucidate the Pharmacological Mechanism of the OSTEOWONDER Capsule for Treating Osteoporosis
por: Fan, Jiashuang, et al.
Publicado: (2022)

Aidi injection reduces doxorubicin-induced cardiotoxicity by inhibiting carbonyl reductase 1 expression
por: Lu, Yuan, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking Validation to Reveal the Pharmacological Mechanisms of Kangai Injection against Colorectal Cancer
por: Zheng, Bo-Bo, et al.
Publicado: (2022)

Uncovering the mechanism of Kang-ai injection for treating intrahepatic cholangiocarcinoma based on network pharmacology, molecular docking, and in vitro validation
por: Song, Fei, et al.
Publicado: (2023)

Network Pharmacology and Molecular Docking Analysis on the Pharmacological Mechanisms of Modified Sanmiaosan in Treating Ulcerative Colitis
por: Wang, Yong, et al.
Publicado: (2022)

Identifying the molecular targets and mechanisms of xuebijing injection for the treatment of COVID-19 via network pharmacology and molecular docking
por: Tianyu, Zhao, et al.
Publicado: (2021)

Research on the Mechanism of Kaempferol for Treating Senile Osteoporosis by Network Pharmacology and Molecular Docking
por: Tang, Fuyu, et al.
Publicado: (2022)

Evaluation of Three Small Molecular Drugs for Targeted Therapy to Treat Nonsmall Cell Lung Cancer
por: Ni, Jun, et al.
Publicado: (2016)

Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis
por: Dou, Dou, et al.
Publicado: (2020)

Exploring the Molecular Mechanism of Qing Guang An Granule in Treating Glaucoma Using Network Pharmacology and Molecular Docking
por: Ou, Chen, et al.
Publicado: (2020)

Discussion on the molecular mechanism of Duhuo Jisheng decoction in treating osteoarthritis based on network pharmacology and molecular docking
por: Yang, Liu, et al.
Publicado: (2022)

The combination of molecular docking and network pharmacology reveals the molecular mechanism of Danggui Niantong decoction in treating gout
por: Liu, Yuan, et al.
Publicado: (2022)

A Bioinformatics Research on Novel Mechanism of Compound Kushen Injection for Treating Breast Cancer by Network Pharmacology and Molecular Docking Verification
por: Liu, Shuyu, et al.
Publicado: (2020)

Mechanism of Danhong Injection in the Treatment of Arrhythmia Based on Network Pharmacology, Molecular Docking, and In Vitro Experiments
por: Yu, Tingting, et al.
Publicado: (2022)

Efficacy of Aidi Injection and Brucea javanica Oil Emulsion Injection in Rectal Cancer during CapeOX Adjuvant Chemotherapy
por: Meng, Wenjun, et al.
Publicado: (2021)

Combined Treatment of Non-Small-Cell Lung Cancer Using Shenyi Capsule and Platinum-Based Chemotherapy: A Meta-Analysis and Systematic Review
por: Xu, Yong, et al.
Publicado: (2020)

Mechanism of Taxanes in the Treatment of Lung Cancer Based on Network Pharmacology and Molecular Docking
por: Zhang, Yajing, et al.
Publicado: (2023)

Evidence of Astragalus injection combined platinum-based chemotherapy in advanced nonsmall cell lung cancer patients: A systematic review and meta-analysis
por: Cao, Ailing, et al.
Publicado: (2019)

Investigating the multi-target pharmacological mechanism of danhong injection acting on unstable angina by combined network pharmacology and molecular docking
por: Guo, Siyu, et al.
Publicado: (2020)

Effect of Aidi Injection plus TACE on Hepatocellular Carcinoma: A Meta-Analysis of Randomized Controlled Trials
por: Dai, Yaoyao, et al.
Publicado: (2018)

Aidi Injection as Adjuvant Drug Combined with Chemotherapy in Treatment of Breast Cancer: A Systematic Meta-Analysis
por: Wu, Chenhao, et al.
Publicado: (2021)

Integration of molecular docking, molecular dynamics and network pharmacology to explore the multi‐target pharmacology of fenugreek against diabetes
por: Luo, Wenfeng, et al.
Publicado: (2023)

Exploring the Molecular Mechanism of Liuwei Dihuang Pills for Treating Diabetic Nephropathy by Combined Network Pharmacology and Molecular Docking
por: Wang, Gaoxiang, et al.
Publicado: (2021)

Exploring the molecular mechanism of Nux Vomica in treating ischemic stroke using network pharmacology and molecular docking methods
por: Zhang, Chengdong, et al.
Publicado: (2023)

Mechanism of Shishiwei Wendan Decoction in the Prevention and Treatment of Lung Adenocarcinoma Using Network Pharmacology and Molecular Docking
por: Li, Xiaofan, et al.
Publicado: (2022)

Exploration of the Molecular Mechanism of Polygonati Rhizoma in the Treatment of Osteoporosis Based on Network Pharmacology and Molecular Docking
por: Zhao, Jinlong, et al.
Publicado: (2022)

Integrating Network Pharmacology, Molecular Docking, and Experimental Validation to Investigate the Mechanism of (−)-Guaiol Against Lung Adenocarcinoma
por: Zeng, Yaoying, et al.
Publicado: (2022)

Network Pharmacology and Molecular Docking Combined to Analyze the Molecular and Pharmacological Mechanism of Pinellia ternata in the Treatment of Hypertension
por: Zhai, Zhaowei, et al.
Publicado: (2021)

Exploring the Mechanism of Danshen against Myelofibrosis by Network Pharmacology and Molecular Docking
por: Li, Jie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_othh31tgk0iv0tqfnu8vmfjip2