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Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma
Testicular cancer is the solid tumor with the greatest incidence in men between 15 and 44 years old. Its main histological type is germ cell tumor, that is divided into seminomatous and non-seminomatous tumors. Seminoma, consisting 55% of testicular cancer, manifests in the fourth decade of men’s li...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Applied Systems srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747564/ https://www.ncbi.nlm.nih.gov/pubmed/36530178 http://dx.doi.org/10.15190/d.2022.8 |
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author | Ioannidis, Orestis Malliora, Anastasia Christidis, Panagiotis Loutzidou, Lydia Anestiadou, Elissavet Symeonidis, Savvas Ouzounidis, Nikolaos Foutsitzis, Vassilis Mantzoros, Ioannis Angelopoulos, Stamatios |
author_facet | Ioannidis, Orestis Malliora, Anastasia Christidis, Panagiotis Loutzidou, Lydia Anestiadou, Elissavet Symeonidis, Savvas Ouzounidis, Nikolaos Foutsitzis, Vassilis Mantzoros, Ioannis Angelopoulos, Stamatios |
author_sort | Ioannidis, Orestis |
collection | PubMed |
description | Testicular cancer is the solid tumor with the greatest incidence in men between 15 and 44 years old. Its main histological type is germ cell tumor, that is divided into seminomatous and non-seminomatous tumors. Seminoma, consisting 55% of testicular cancer, manifests in the fourth decade of men’s life and a rare type of it is the anaplastic seminoma (5% to 15% of testicular seminoma). Diagnosis is based on clinical examination, testicular ultrasound, magnetic resonance imaging, tumor markers measurement and pathological examination, while treatment of choice is radical orchiectomy, with or without retroperitoneal lymphadenectomy, potentially followed by radiotherapy or chemotherapy. We present the case of a 36-year-old male patient, whose father suffered from anaplastic seminoma and visited the hospital due to a painless hydrocele. The testicle was swollen and hard on palpation, while cytological examination of the drained fluid detected neoplasm, potentially seminoma. Tumor markers measurement, as well as abdominal and pelvic computerized tomography scans, were evaluated and the patient was staged as IIA, according to the American Joint Commission on Cancer. Radical orchiectomy with high ligation of the seminal vesicle was performed and the pathological examination showed anaplastic testicular seminoma. Postoperatively, four cycles of chemotherapy with bleomycin, etoposide and platinum (BEP) were performed and no signs of recurrence were present after 1 year. In conclusion, anaplastic seminoma has a good prognosis and is suggested to be treated with radical orchiectomy, with or without retroperitoneal lymphadenectomy, potentially followed by radiotherapy or chemotherapy. |
format | Online Article Text |
id | pubmed-9747564 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Applied Systems srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-97475642022-12-15 Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma Ioannidis, Orestis Malliora, Anastasia Christidis, Panagiotis Loutzidou, Lydia Anestiadou, Elissavet Symeonidis, Savvas Ouzounidis, Nikolaos Foutsitzis, Vassilis Mantzoros, Ioannis Angelopoulos, Stamatios Discoveries (Craiova) Original Article Testicular cancer is the solid tumor with the greatest incidence in men between 15 and 44 years old. Its main histological type is germ cell tumor, that is divided into seminomatous and non-seminomatous tumors. Seminoma, consisting 55% of testicular cancer, manifests in the fourth decade of men’s life and a rare type of it is the anaplastic seminoma (5% to 15% of testicular seminoma). Diagnosis is based on clinical examination, testicular ultrasound, magnetic resonance imaging, tumor markers measurement and pathological examination, while treatment of choice is radical orchiectomy, with or without retroperitoneal lymphadenectomy, potentially followed by radiotherapy or chemotherapy. We present the case of a 36-year-old male patient, whose father suffered from anaplastic seminoma and visited the hospital due to a painless hydrocele. The testicle was swollen and hard on palpation, while cytological examination of the drained fluid detected neoplasm, potentially seminoma. Tumor markers measurement, as well as abdominal and pelvic computerized tomography scans, were evaluated and the patient was staged as IIA, according to the American Joint Commission on Cancer. Radical orchiectomy with high ligation of the seminal vesicle was performed and the pathological examination showed anaplastic testicular seminoma. Postoperatively, four cycles of chemotherapy with bleomycin, etoposide and platinum (BEP) were performed and no signs of recurrence were present after 1 year. In conclusion, anaplastic seminoma has a good prognosis and is suggested to be treated with radical orchiectomy, with or without retroperitoneal lymphadenectomy, potentially followed by radiotherapy or chemotherapy. Applied Systems srl 2022-06-30 /pmc/articles/PMC9747564/ /pubmed/36530178 http://dx.doi.org/10.15190/d.2022.8 Text en Copyright © 2022, Ioannidis O et al., Applied Systems and Discoveries Journals. https://creativecommons.org/licenses/by/4.0/This article is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited and it is not used for commercial purposes. |
spellingShingle | Original Article Ioannidis, Orestis Malliora, Anastasia Christidis, Panagiotis Loutzidou, Lydia Anestiadou, Elissavet Symeonidis, Savvas Ouzounidis, Nikolaos Foutsitzis, Vassilis Mantzoros, Ioannis Angelopoulos, Stamatios Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title | Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title_full | Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title_fullStr | Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title_full_unstemmed | Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title_short | Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
title_sort | anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747564/ https://www.ncbi.nlm.nih.gov/pubmed/36530178 http://dx.doi.org/10.15190/d.2022.8 |
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