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Strychnos alkaloids: total synthesis, characterization, DFT investigations, and molecular docking with AChE, BuChE, and HSA

An efficient five steps, the protection-deprotection synthetic a novel synthetic routes to(±) noruleine (±)-uleine, are reported starting from tetrahydrocarbazole fused monoalkyl nitrile at C-2 position that is prepared on multigram scale from 2-(3-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)ace...

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Detalles Bibliográficos
Autores principales: Uludag, Nesimi, Üstün, Elvan, Serdaroğlu, Goncagül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747589/
https://www.ncbi.nlm.nih.gov/pubmed/36531635
http://dx.doi.org/10.1016/j.heliyon.2022.e11990