Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission

Fission protein 1 (FIS1) and dynamin-related protein 1 (DRP1) were initially described as being evolutionarily conserved for mitochondrial fission, yet in humans the role of FIS1 in this process is unclear and disputed by many. In budding yeast where Fis1p helps to recruit the DRP1 ortholog from the...

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Detalles Bibliográficos
Autores principales: Egner, John M., Nolden, Kelsey A., Harwig, Megan Cleland, Bonate, Ryan P., De Anda, Jaime, Tessmer, Maxx H., Noey, Elizabeth L., Ihenacho, Ugochukwu K., Liu, Ziwen, Peterson, Francis C., Wong, Gerard C.L., Widlansky, Michael E., Hill, R. Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747602/
https://www.ncbi.nlm.nih.gov/pubmed/36272645
http://dx.doi.org/10.1016/j.jbc.2022.102620

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