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Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction

Driving systems out of equilibrium under feedback control is characteristic for living systems, where homeostasis and dissipative signal transduction facilitate complex responses. This feature not only inspires dissipative dynamic functionalities in synthetic systems but also poses great challenges...

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Autores principales: Zhang, Hang, Zeng, Hao, Eklund, Amanda, Guo, Hongshuang, Priimagi, Arri, Ikkala, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747616/
https://www.ncbi.nlm.nih.gov/pubmed/36443600
http://dx.doi.org/10.1038/s41565-022-01241-x
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author Zhang, Hang
Zeng, Hao
Eklund, Amanda
Guo, Hongshuang
Priimagi, Arri
Ikkala, Olli
author_facet Zhang, Hang
Zeng, Hao
Eklund, Amanda
Guo, Hongshuang
Priimagi, Arri
Ikkala, Olli
author_sort Zhang, Hang
collection PubMed
description Driving systems out of equilibrium under feedback control is characteristic for living systems, where homeostasis and dissipative signal transduction facilitate complex responses. This feature not only inspires dissipative dynamic functionalities in synthetic systems but also poses great challenges in designing novel pathways. Here we report feedback-controlled systems comprising two coupled hydrogels driven by constant light, where the system can be tuned to undergo stable homeostatic self-oscillations or damped steady states of temperature. We demonstrate that stable temperature oscillations can be utilized for dynamic colours and cargo transport, whereas damped steady states enable signal transduction pathways. Here mechanical triggers cause temperature changes that lead to responses such as bending motions inspired by the single-touch mechanoresponse in Mimosa pudica and the frequency-gated snapping motion inspired by the plant arithmetic in the Venus flytrap. The proposed concepts suggest generalizable feedback pathways for dissipative dynamic materials and interactive soft robotics.
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spelling pubmed-97476162022-12-15 Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction Zhang, Hang Zeng, Hao Eklund, Amanda Guo, Hongshuang Priimagi, Arri Ikkala, Olli Nat Nanotechnol Article Driving systems out of equilibrium under feedback control is characteristic for living systems, where homeostasis and dissipative signal transduction facilitate complex responses. This feature not only inspires dissipative dynamic functionalities in synthetic systems but also poses great challenges in designing novel pathways. Here we report feedback-controlled systems comprising two coupled hydrogels driven by constant light, where the system can be tuned to undergo stable homeostatic self-oscillations or damped steady states of temperature. We demonstrate that stable temperature oscillations can be utilized for dynamic colours and cargo transport, whereas damped steady states enable signal transduction pathways. Here mechanical triggers cause temperature changes that lead to responses such as bending motions inspired by the single-touch mechanoresponse in Mimosa pudica and the frequency-gated snapping motion inspired by the plant arithmetic in the Venus flytrap. The proposed concepts suggest generalizable feedback pathways for dissipative dynamic materials and interactive soft robotics. Nature Publishing Group UK 2022-11-28 2022 /pmc/articles/PMC9747616/ /pubmed/36443600 http://dx.doi.org/10.1038/s41565-022-01241-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Zhang, Hang
Zeng, Hao
Eklund, Amanda
Guo, Hongshuang
Priimagi, Arri
Ikkala, Olli
Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title_full Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title_fullStr Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title_full_unstemmed Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title_short Feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
title_sort feedback-controlled hydrogels with homeostatic oscillations and dissipative signal transduction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747616/
https://www.ncbi.nlm.nih.gov/pubmed/36443600
http://dx.doi.org/10.1038/s41565-022-01241-x
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