Characteristics and Survival Results of Peritoneal Dialysis Patients Suffering from COVID-19 in Turkey: A Multicenter National Study

INTRODUCTION: We aimed to study the characteristics of peritoneal dialysis (PD) patients with coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome. METHODS: In this multicenter national study...

Descripción completa

Detalles Bibliográficos
Autores principales: Gursu, Meltem, Ozturk, Savas, Arici, Mustafa, Sahin, Idris, Gokcay Bek, Sibel, Yilmaz, Murvet, Koyuncu, Sumeyra, Karahisar Sirali, Semahat, Ural, Zeynep, Dursun, Belda, Yuksel, Enver, Uzun, Sami, Sipahi, Savaş, Ahbap, Elbis, Artan, Ayse Serra, Altunoren, Orcun, Tunca, Onur, Ayar, Yavuz, Gok Oguz, Ebru, Yilmaz, Zulfukar, Kahvecioglu, Serdar, Asicioglu, Ebru, Oruc, Aysegul, Altiparmak, Mehmet Riza, Aydin, Zeki, Huddam, Bulent, Dolarslan, Murside Esra, Azak, Alper, Bakırdogen, Serkan, Yalcin, Ahmet Ugur, Karadag, Serhat, Ulu, Memnune Sena, Gungor, Ozkan, Ari Bakir, Elif, Odabas, Ali Rıza, Seyahi, Nurhan, Yildiz, Alaattin, Ates, Kenan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747730/
https://www.ncbi.nlm.nih.gov/pubmed/36099904
http://dx.doi.org/10.1159/000526909
Descripción
Sumario:INTRODUCTION: We aimed to study the characteristics of peritoneal dialysis (PD) patients with coronavirus disease-19 (COVID-19), determine the short-term mortality and other medical complications, and delineate the factors associated with COVID-19 outcome. METHODS: In this multicenter national study, we included PD patients with confirmed COVID-19 from 27 centers. The baseline demographic, clinical, laboratory, and radiological data and outcomes at the end of the first month were recorded. RESULTS: We enrolled 142 COVID-19 patients (median age: 52 years). 58.2% of patients had mild disease at diagnosis. Lung involvement was detected in 60.8% of patients. Eighty-three (58.4%) patients were hospitalized, 31 (21.8%) patients were admitted to intensive care unit and 24 needed mechanical ventilation. Fifteen (10.5%) patients were switched to hemodialysis and hemodiafiltration was performed for four (2.8%) patients. Persisting pulmonary symptoms (n = 27), lower respiratory system infection (n = 12), rehospitalization for any reason (n = 24), malnutrition (n = 6), hypervolemia (n = 13), peritonitis (n = 7), ultrafiltration failure (n = 7), and in PD modality change (n = 8) were reported in survivors. Twenty-six patients (18.31%) died in the first month of diagnosis. The non-survivor group was older, comorbidities were more prevalent. Fever, dyspnea, cough, serious-vital disease at presentation, bilateral pulmonary involvement, and pleural effusion were more frequent among non-survivors. Age (OR: 1.102; 95% CI: 1.032–1.117; p: 0.004), moderate-severe clinical disease at presentation (OR: 26.825; 95% CI: 4.578–157.172; p < 0.001), and baseline CRP (OR: 1.008; 95% CI; 1,000–1.016; p: 0.040) were associated with first-month mortality in multivariate analysis. DISCUSSION/CONCLUSIONS: Early mortality rate and medical complications are quite high in PD patients with COVID-19. Age, clinical severity of COVID-19, and baseline CRP level are the independent parameters associated with mortality.

Ejemplares similares