Mesenchymal stromal cells donate mitochondria to articular chondrocytes exposed to mitochondrial, environmental, and mechanical stress

Articular cartilage has limited healing capacity and no drugs are available that can prevent or slow the development of osteoarthritis (OA) after joint injury. Mesenchymal stromal cell (MSC)-based regenerative therapies for OA are increasingly common, but questions regarding their mechanisms of acti...

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Detalles Bibliográficos
Autores principales: Fahey, Megan, Bennett, Maureen, Thomas, Matthew, Montney, Kaylee, Vivancos-Koopman, Irene, Pugliese, Brenna, Browning, Lindsay, Bonassar, Lawrence J., Delco, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747781/
https://www.ncbi.nlm.nih.gov/pubmed/36513773
http://dx.doi.org/10.1038/s41598-022-25844-5

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