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SMOC2 promotes aggressive behavior of fibroblast-like synoviocytes in rheumatoid arthritis through transcriptional and post-transcriptional regulating MYO1C

Fibroblast-like synoviocytes (FLSs), play a key role in perpetuating synovial inflammation and bone erosion in rheumatoid arthritis (RA), however, the underlying mechanism(s) of RA FLSs activation and aggression remain unclear. Identifying endogenous proteins that selectively target FLSs is urgently...

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Detalles Bibliográficos
Autores principales: Liu, Di, Li, Ruiru, Xu, Siqi, Shi, Maohua, Kuang, Yu, Wang, Jingnan, Shen, Chuyu, Qiu, Qian, Liang, Liuqin, Xiao, Youjun, Xu, Hanshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747908/
https://www.ncbi.nlm.nih.gov/pubmed/36513634
http://dx.doi.org/10.1038/s41419-022-05479-0