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Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis

Atherosclerosis is reported to be a risk factor for the severity of idiopathic sudden sensorineural hearing loss (ISSNHL). We evaluated the hypothesis that atherosclerosis affects the hearing thresholds of both the affected and healthy sides of ISSNHL patients. We conducted multivariate analyses on...

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Autores principales: Tsuzuki, Nobuyoshi, Wasano, Koichiro, Oishi, Naoki, Hentona, Ko, Shimanuki, Marie, Nishiyama, Takanori, Hiraga, Yoshihiko, Ueno, Masafumi, Suzuki, Narihisa, Shinden, Seiichi, Ogawa, Kaoru, Ozawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747959/
https://www.ncbi.nlm.nih.gov/pubmed/36513737
http://dx.doi.org/10.1038/s41598-022-25593-5
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author Tsuzuki, Nobuyoshi
Wasano, Koichiro
Oishi, Naoki
Hentona, Ko
Shimanuki, Marie
Nishiyama, Takanori
Hiraga, Yoshihiko
Ueno, Masafumi
Suzuki, Narihisa
Shinden, Seiichi
Ogawa, Kaoru
Ozawa, Hiroyuki
author_facet Tsuzuki, Nobuyoshi
Wasano, Koichiro
Oishi, Naoki
Hentona, Ko
Shimanuki, Marie
Nishiyama, Takanori
Hiraga, Yoshihiko
Ueno, Masafumi
Suzuki, Narihisa
Shinden, Seiichi
Ogawa, Kaoru
Ozawa, Hiroyuki
author_sort Tsuzuki, Nobuyoshi
collection PubMed
description Atherosclerosis is reported to be a risk factor for the severity of idiopathic sudden sensorineural hearing loss (ISSNHL). We evaluated the hypothesis that atherosclerosis affects the hearing thresholds of both the affected and healthy sides of ISSNHL patients. We conducted multivariate analyses on retrospectively collected data of patients with ISSNHL (N = 762) to evaluate the relationship between known factors linked to atherosclerosis and hearing thresholds on affected and healthy sides and whether these factors are prognostic for hearing recovery. Older ages, vertigo or dizziness, diabetes mellitus, and congestive heart failure were significantly related to higher hearing thresholds on the affected side. Older ages, male, and vascular disease were significantly related to higher hearing thresholds on the healthy side. Vertigo or dizziness, severe hearing loss and hearing loss at high frequencies on the affected side, higher hearing thresholds on the healthy side, regular anticoagulant medication, and delayed steroid treatment were significantly related to lack of recovery. Since several atherosclerosis-related factors are associated with higher hearing thresholds on both affected and healthy sides in ISSNHL and higher hearing thresholds on the healthy side predict poorer prognosis, diagnosis, and predicting prognosis of ISSNHL may benefit from rigorous evaluation of patients’ cardiovascular comorbidities and hearing levels on both the healthy and affected sides.
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spelling pubmed-97479592022-12-15 Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis Tsuzuki, Nobuyoshi Wasano, Koichiro Oishi, Naoki Hentona, Ko Shimanuki, Marie Nishiyama, Takanori Hiraga, Yoshihiko Ueno, Masafumi Suzuki, Narihisa Shinden, Seiichi Ogawa, Kaoru Ozawa, Hiroyuki Sci Rep Article Atherosclerosis is reported to be a risk factor for the severity of idiopathic sudden sensorineural hearing loss (ISSNHL). We evaluated the hypothesis that atherosclerosis affects the hearing thresholds of both the affected and healthy sides of ISSNHL patients. We conducted multivariate analyses on retrospectively collected data of patients with ISSNHL (N = 762) to evaluate the relationship between known factors linked to atherosclerosis and hearing thresholds on affected and healthy sides and whether these factors are prognostic for hearing recovery. Older ages, vertigo or dizziness, diabetes mellitus, and congestive heart failure were significantly related to higher hearing thresholds on the affected side. Older ages, male, and vascular disease were significantly related to higher hearing thresholds on the healthy side. Vertigo or dizziness, severe hearing loss and hearing loss at high frequencies on the affected side, higher hearing thresholds on the healthy side, regular anticoagulant medication, and delayed steroid treatment were significantly related to lack of recovery. Since several atherosclerosis-related factors are associated with higher hearing thresholds on both affected and healthy sides in ISSNHL and higher hearing thresholds on the healthy side predict poorer prognosis, diagnosis, and predicting prognosis of ISSNHL may benefit from rigorous evaluation of patients’ cardiovascular comorbidities and hearing levels on both the healthy and affected sides. Nature Publishing Group UK 2022-12-13 /pmc/articles/PMC9747959/ /pubmed/36513737 http://dx.doi.org/10.1038/s41598-022-25593-5 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Tsuzuki, Nobuyoshi
Wasano, Koichiro
Oishi, Naoki
Hentona, Ko
Shimanuki, Marie
Nishiyama, Takanori
Hiraga, Yoshihiko
Ueno, Masafumi
Suzuki, Narihisa
Shinden, Seiichi
Ogawa, Kaoru
Ozawa, Hiroyuki
Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title_full Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title_fullStr Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title_full_unstemmed Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title_short Association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
title_sort association between atherosclerosis, hearing recovery, and hearing in the healthy ear in idiopathic sudden sensorineural hearing loss: a retrospective chart analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747959/
https://www.ncbi.nlm.nih.gov/pubmed/36513737
http://dx.doi.org/10.1038/s41598-022-25593-5
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