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Structure-function studies reveal ComEA contains an oligomerization domain essential for transformation in gram-positive bacteria

An essential step in bacterial transformation is the uptake of DNA into the periplasm, across the thick peptidoglycan cell wall of Gram-positive bacteria, or the outer membrane and thin peptidoglycan layer of Gram-negative bacteria. ComEA, a DNA-binding protein widely conserved in transformable bact...

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Detalles Bibliográficos
Autores principales: Ahmed, Ishtiyaq, Hahn, Jeanette, Henrickson, Amy, Khaja, Faisal Tarique, Demeler, Borries, Dubnau, David, Neiditch, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747964/
https://www.ncbi.nlm.nih.gov/pubmed/36513643
http://dx.doi.org/10.1038/s41467-022-35129-0

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