Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation

Cellular metabolism influences immune cell function, with mitochondrial fatty acid β-oxidation and oxidative phosphorylation required for multiple immune cell phenotypes. Carnitine palmitoyltransferase 1a (Cpt1a) is considered the rate-limiting enzyme for mitochondrial metabolism of long-chain fatty...

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Detalles Bibliográficos
Autores principales: Pham, Ly, Komalavilas, Padmini, Eddie, Alex M., Thayer, Timothy E., Greenwood, Dalton L., Liu, Ken H., Weinberg, Jaclyn, Patterson, Andrew, Fessel, Joshua P., Boyd, Kelli L., Schafer, Jenny C., Kuck, Jamie L., Shaver, Aaron C., Flaherty, David K., Matlock, Brittany K., Wijers, Christiaan D. M., Serezani, C. Henrique, Jones, Dean P., Brittain, Evan L., Rathmell, Jeffrey C., Noto, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747976/
https://www.ncbi.nlm.nih.gov/pubmed/36513703
http://dx.doi.org/10.1038/s42003-022-04339-z

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