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Gapless genome assembly of East Asian finless porpoise

In recent years, conservation efforts have increased for rare and endangered aquatic wildlife, especially cetaceans. However, the East Asian finless porpoise (Neophocaena asiaeorientalis sunameri), which has a wide distribution in China, has received far less attention and protection. As an endanger...

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Detalles Bibliográficos
Autores principales: Yin, Denghua, Chen, Chunhai, Lin, Danqing, Zhang, Jialu, Ying, Congping, Liu, Yan, Liu, Wang, Cao, Zhichen, Zhao, Chenxi, Wang, Chenhe, Liang, Liping, Xu, Pao, Jian, Jianbo, Liu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747978/
https://www.ncbi.nlm.nih.gov/pubmed/36513679
http://dx.doi.org/10.1038/s41597-022-01868-4
Descripción
Sumario:In recent years, conservation efforts have increased for rare and endangered aquatic wildlife, especially cetaceans. However, the East Asian finless porpoise (Neophocaena asiaeorientalis sunameri), which has a wide distribution in China, has received far less attention and protection. As an endangered small cetacean, the lack of a chromosomal-level reference for the East Asian finless porpoise limits our understanding of its population genetics and conservation biology. To address this issue, we combined PacBio HiFi long reads and Hi-C sequencing data to generate a gapless genome of the East Asian finless porpoise that is approximately 2.5 Gb in size over its 21 autosomes and two sex chromosomes (X and Y). A total of 22,814 protein-coding genes were predicted where ~97.31% were functionally annotated. This high-quality genome assembly of East Asian finless porpoise will not only provide new resources for the comparative genomics of cetaceans and conservation biology of threatened species, but also lay a foundation for more speciation, ecology, and evolutionary studies.