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Epigenetic priming of immune/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury
Prenatal inflammatory insults accompany prematurity and provoke diffuse white matter injury (DWMI), which is associated with increased risk of neurodevelopmental pathologies, including autism spectrum disorders. DWMI results from maturation arrest of oligodendrocyte precursor cells (OPCs), a process...
Autores principales: | Schang, Anne-Laure, Van Steenwinckel, Juliette, Ioannidou, Zoi S., Lipecki, Julia, Rich-Griffin, Charlotte, Woolley-Allen, Kate, Dyer, Nigel, Le Charpentier, Tifenn, Schäfer, Patrick, Fleiss, Bobbi, Ott, Sascha, Sabéran-Djoneidi, Délara, Mezger, Valérie, Gressens, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748018/ https://www.ncbi.nlm.nih.gov/pubmed/36513635 http://dx.doi.org/10.1038/s41419-022-05483-4 |
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