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Bone morphogenetic protein 4 inhibits rat stem/progenitor Leydig cell development and regeneration via SMAD-dependent and SMAD-independent signaling

Bone morphogenetic protein 4 (BMP4) is an important member of the transforming growth factor-β superfamily. BMP4 is expressed in the Leydig cell lineage. We hypothesized that BMP4 might regulate the development of stem/progenitor Leydig cells. The BMP4 receptors, BMPR1A, BMPR1B, and BMPR2 were found...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoheng, Fang, Yinghui, Chen, Lanlan, Quan, Hehua, Wang, Yiyan, Ge, Ren-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748027/ https://www.ncbi.nlm.nih.gov/pubmed/36513649 http://dx.doi.org/10.1038/s41419-022-05471-8

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