Deep brain stimulation creates informational lesion through membrane depolarization in mouse hippocampus

Deep brain stimulation (DBS) is a promising neuromodulation therapy, but the neurophysiological mechanisms of DBS remain unclear. In awake mice, we performed high-speed membrane voltage fluorescence imaging of individual hippocampal CA1 neurons during DBS delivered at 40 Hz or 140 Hz, free of electr...

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Detalles Bibliográficos
Autores principales: Lowet, Eric, Kondabolu, Krishnakanth, Zhou, Samuel, Mount, Rebecca A., Wang, Yangyang, Ravasio, Cara R., Han, Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748039/
https://www.ncbi.nlm.nih.gov/pubmed/36513664
http://dx.doi.org/10.1038/s41467-022-35314-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748039/
https://www.ncbi.nlm.nih.gov/pubmed/36513664
http://dx.doi.org/10.1038/s41467-022-35314-1

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