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Deep brain stimulation creates informational lesion through membrane depolarization in mouse hippocampus
Deep brain stimulation (DBS) is a promising neuromodulation therapy, but the neurophysiological mechanisms of DBS remain unclear. In awake mice, we performed high-speed membrane voltage fluorescence imaging of individual hippocampal CA1 neurons during DBS delivered at 40 Hz or 140 Hz, free of electr...
Autores principales: | Lowet, Eric, Kondabolu, Krishnakanth, Zhou, Samuel, Mount, Rebecca A., Wang, Yangyang, Ravasio, Cara R., Han, Xue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748039/ https://www.ncbi.nlm.nih.gov/pubmed/36513664 http://dx.doi.org/10.1038/s41467-022-35314-1 |
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