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Serological survey of SARS-CoV-2 in companion animals in China

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted from human to companion animals. The national wide serological surveillance against SARS-CoV-2 was conducted among pet animals, mainly in cats and dogs, 1 year after the first outbreak of COVID-19 in China. All sera were...

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Autores principales: Wang, Aiping, Zhu, Xifang, Chen, Yumei, Sun, Yaning, Liu, Hongliang, Ding, Peiyang, Zhou, Jingming, Liu, Yankai, Liang, Chao, Yin, Jiajia, Zhang, Gaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748147/
https://www.ncbi.nlm.nih.gov/pubmed/36532346
http://dx.doi.org/10.3389/fvets.2022.986619
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author Wang, Aiping
Zhu, Xifang
Chen, Yumei
Sun, Yaning
Liu, Hongliang
Ding, Peiyang
Zhou, Jingming
Liu, Yankai
Liang, Chao
Yin, Jiajia
Zhang, Gaiping
author_facet Wang, Aiping
Zhu, Xifang
Chen, Yumei
Sun, Yaning
Liu, Hongliang
Ding, Peiyang
Zhou, Jingming
Liu, Yankai
Liang, Chao
Yin, Jiajia
Zhang, Gaiping
author_sort Wang, Aiping
collection PubMed
description Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted from human to companion animals. The national wide serological surveillance against SARS-CoV-2 was conducted among pet animals, mainly in cats and dogs, 1 year after the first outbreak of COVID-19 in China. All sera were tested for SARS-CoV-2 IgG antibodies using an indirect enzyme linked immunosorbent assay (ELISA) based on the receptor binding domain (RBD) of spike protein. This late survey takes advantage of the short duration of the serological response in these animals to track recent episode of transmission. A total of 20,592 blood samples were obtained from 25 provinces across 7 geographical regions. The overall seroprevalence of SARS-CoV-2 infections in cats was 0.015% (2/13397; 95% confidence intervals (CI): 0.0, 0.1). The virus infections in cats were only detected in Central (Hubei, 0.375%) and Eastern China (Zhejiang, 0.087%) with a seroprevalence estimated at 0.090 and 0.020%, respectively. In dogs, the seroprevalence of SARS-CoV-2 infections was 0.014% (1/7159; 95% CI: 0.0, 0.1) in the entire nation, seropositive samples were limited to Beijing (0.070%) of Northern China with a prevalence of 0.054%. No seropositive cases were discovered in other geographic regions, nor in other companion animals analyzed in this study. These data reveal the circulation of SARS-CoV-2 in companion animals, although transmission of the virus to domestic cats and dogs is low in China, continuous monitoring is helpful for the better understand of the virus transmission status and the effect on animals.
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spelling pubmed-97481472022-12-15 Serological survey of SARS-CoV-2 in companion animals in China Wang, Aiping Zhu, Xifang Chen, Yumei Sun, Yaning Liu, Hongliang Ding, Peiyang Zhou, Jingming Liu, Yankai Liang, Chao Yin, Jiajia Zhang, Gaiping Front Vet Sci Veterinary Science Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted from human to companion animals. The national wide serological surveillance against SARS-CoV-2 was conducted among pet animals, mainly in cats and dogs, 1 year after the first outbreak of COVID-19 in China. All sera were tested for SARS-CoV-2 IgG antibodies using an indirect enzyme linked immunosorbent assay (ELISA) based on the receptor binding domain (RBD) of spike protein. This late survey takes advantage of the short duration of the serological response in these animals to track recent episode of transmission. A total of 20,592 blood samples were obtained from 25 provinces across 7 geographical regions. The overall seroprevalence of SARS-CoV-2 infections in cats was 0.015% (2/13397; 95% confidence intervals (CI): 0.0, 0.1). The virus infections in cats were only detected in Central (Hubei, 0.375%) and Eastern China (Zhejiang, 0.087%) with a seroprevalence estimated at 0.090 and 0.020%, respectively. In dogs, the seroprevalence of SARS-CoV-2 infections was 0.014% (1/7159; 95% CI: 0.0, 0.1) in the entire nation, seropositive samples were limited to Beijing (0.070%) of Northern China with a prevalence of 0.054%. No seropositive cases were discovered in other geographic regions, nor in other companion animals analyzed in this study. These data reveal the circulation of SARS-CoV-2 in companion animals, although transmission of the virus to domestic cats and dogs is low in China, continuous monitoring is helpful for the better understand of the virus transmission status and the effect on animals. Frontiers Media S.A. 2022-11-30 /pmc/articles/PMC9748147/ /pubmed/36532346 http://dx.doi.org/10.3389/fvets.2022.986619 Text en Copyright © 2022 Wang, Zhu, Chen, Sun, Liu, Ding, Zhou, Liu, Liang, Yin and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Wang, Aiping
Zhu, Xifang
Chen, Yumei
Sun, Yaning
Liu, Hongliang
Ding, Peiyang
Zhou, Jingming
Liu, Yankai
Liang, Chao
Yin, Jiajia
Zhang, Gaiping
Serological survey of SARS-CoV-2 in companion animals in China
title Serological survey of SARS-CoV-2 in companion animals in China
title_full Serological survey of SARS-CoV-2 in companion animals in China
title_fullStr Serological survey of SARS-CoV-2 in companion animals in China
title_full_unstemmed Serological survey of SARS-CoV-2 in companion animals in China
title_short Serological survey of SARS-CoV-2 in companion animals in China
title_sort serological survey of sars-cov-2 in companion animals in china
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748147/
https://www.ncbi.nlm.nih.gov/pubmed/36532346
http://dx.doi.org/10.3389/fvets.2022.986619
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