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A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab

Thoracic SMARCA4‐deficient undifferentiated tumors are rare, with poor prognosis. A 73‐year‐old man presented to our hospital with dyspnea. Computed tomography‐guided biopsy revealed a SMARCA4‐deficient undifferentiated tumor. The patient was treated with combination ipilimumab‐nivolumab. The tumor...

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Autores principales: Nakano, Yoshio, Sekinada, Daisuke, Kuze, Yusuke, Okamoto, Norio, Gohma, Iwao, Yasuhara, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748223/
https://www.ncbi.nlm.nih.gov/pubmed/36523385
http://dx.doi.org/10.1002/ccr3.6745
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author Nakano, Yoshio
Sekinada, Daisuke
Kuze, Yusuke
Okamoto, Norio
Gohma, Iwao
Yasuhara, Yumiko
author_facet Nakano, Yoshio
Sekinada, Daisuke
Kuze, Yusuke
Okamoto, Norio
Gohma, Iwao
Yasuhara, Yumiko
author_sort Nakano, Yoshio
collection PubMed
description Thoracic SMARCA4‐deficient undifferentiated tumors are rare, with poor prognosis. A 73‐year‐old man presented to our hospital with dyspnea. Computed tomography‐guided biopsy revealed a SMARCA4‐deficient undifferentiated tumor. The patient was treated with combination ipilimumab‐nivolumab. The tumor reduced in size after two courses.
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spelling pubmed-97482232022-12-14 A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab Nakano, Yoshio Sekinada, Daisuke Kuze, Yusuke Okamoto, Norio Gohma, Iwao Yasuhara, Yumiko Clin Case Rep Case Report Thoracic SMARCA4‐deficient undifferentiated tumors are rare, with poor prognosis. A 73‐year‐old man presented to our hospital with dyspnea. Computed tomography‐guided biopsy revealed a SMARCA4‐deficient undifferentiated tumor. The patient was treated with combination ipilimumab‐nivolumab. The tumor reduced in size after two courses. John Wiley and Sons Inc. 2022-12-13 /pmc/articles/PMC9748223/ /pubmed/36523385 http://dx.doi.org/10.1002/ccr3.6745 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nakano, Yoshio
Sekinada, Daisuke
Kuze, Yusuke
Okamoto, Norio
Gohma, Iwao
Yasuhara, Yumiko
A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title_full A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title_fullStr A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title_full_unstemmed A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title_short A case of thoracic SMARCA4‐Deficient undifferentiated tumor successfully treated with combination Ipilimumab–Nivolumab
title_sort case of thoracic smarca4‐deficient undifferentiated tumor successfully treated with combination ipilimumab–nivolumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748223/
https://www.ncbi.nlm.nih.gov/pubmed/36523385
http://dx.doi.org/10.1002/ccr3.6745
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