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Systematic comparison of family history and polygenic risk across 24 common diseases

Family history is the standard indirect measure of inherited susceptibility in clinical care, whereas polygenic risk scores (PRSs) have more recently demonstrated potential for more directly capturing genetic risk in many diseases. Few studies have systematically compared how these overlap and compl...

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Detalles Bibliográficos
Autores principales:	Mars, Nina, Lindbohm, Joni V., della Briotta Parolo, Pietro, Widén, Elisabeth, Kaprio, Jaakko, Palotie, Aarno, Ripatti, Samuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748261/ https://www.ncbi.nlm.nih.gov/pubmed/36347255 http://dx.doi.org/10.1016/j.ajhg.2022.10.009

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