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miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2

Mitochondrial oxidative stress and dysfunction are major pathogenic features of cardiac injury induced by ischemia/reperfusion (I/R). MicroRNA-141 (miR-141) has been implicated in the mitochondrial dysfunction in cell-based models of oxidant stress. Thus, the main aim of the present study was to sys...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Wang, Yaqiao, Wu, Kehan, Liu, Runmin, Wang, Hao, Yao, Yongwei, Kvietys, Peter, Rui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748642/
https://www.ncbi.nlm.nih.gov/pubmed/36561976
http://dx.doi.org/10.3892/etm.2022.11699