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Characterizing Variants of Unknown Significance of the PTEN tumour suppressorHomolog DAF-18

Insulin and insulin-like growth factor signaling (IIS) is an anabolic pathway conserved among humans and Caenorhabditis elegans . In humans, the tumour suppressor protein Phosphatase and Tensin Homolog (PTEN) inhibits IIS, preventing excessive growth. PTEN variants are associated with disease, but h...

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Detalles Bibliográficos
Autores principales:	Ermakova, Glafira, Hou, Chadwick, Boudreau, Jeffrey, Bendena, William G, Chin-Sang, Ian D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Caltech Library 2022
Materias:	New Finding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748723/ https://www.ncbi.nlm.nih.gov/pubmed/36530472 http://dx.doi.org/10.17912/micropub.biology.000689

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