Genome-Wide Association Studies Identify an Association of Transferrin Binding Protein B Variation and Invasive Serogroup Y Meningococcal Disease in Older Adults

BACKGROUND: Neisseria meningitidis serogroup Y, especially ST-23 clonal complex (Y:cc23), represents a larger proportion of invasive meningococcal disease (IMD) in older adults compared to younger individuals. This study explored the meningococcal genetic variation underlying this association. METHO...

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Detalles Bibliográficos
Autores principales: Maynard-Smith, Laura, Derrick, Jeremy P, Borrow, Ray, Lucidarme, Jay, Maiden, Martin C J, Heyderman, Robert S, Harrison, Odile B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748998/
https://www.ncbi.nlm.nih.gov/pubmed/36322504
http://dx.doi.org/10.1093/infdis/jiac430

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