Cargando…
Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis
Acute upper or lower Gastrointestinal bleeding (GIB) is a clinical emergency in which transfusion can be lifesaving. An individualized and restrictive transfusion strategy is recommended. This study aims to analyze and evaluate GIB transfusion practices during one year in a large tertiary hospital i...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749046/ https://www.ncbi.nlm.nih.gov/pubmed/36503291 http://dx.doi.org/10.1177/10760296221087219 |
_version_ | 1784849960312766464 |
---|---|
author | Costa, Ana Palricas Pereira, Carla Leal Garção, Ana Rodrigues, Anabela |
author_facet | Costa, Ana Palricas Pereira, Carla Leal Garção, Ana Rodrigues, Anabela |
author_sort | Costa, Ana Palricas |
collection | PubMed |
description | Acute upper or lower Gastrointestinal bleeding (GIB) is a clinical emergency in which transfusion can be lifesaving. An individualized and restrictive transfusion strategy is recommended. This study aims to analyze and evaluate GIB transfusion practices during one year in a large tertiary hospital in Lisbon, Portugal. All patients with GIB and transfusion support during 2014 were identified and clinical data collected and statistically treated. There were 1005 GIB transfusion episodes, in a total of 494 patients. Upper GIB was more common. The median haemoglobin concentration that triggered RBC transfusion was 7,6 g/dL with a median of 2 RBC per episode. In 21,9% of episodes, RBC were used in combination with other therapies, in 70,8%, only RBC were administered and in 7,3% RBC were not used at all. In the subgroup of patients receiving FC and/or PCC there were higher median of blood products transfused: RBC (3 17 units), FFP (3 units), PC (1 unit). In a large percentage of the transfusion episodes for GIB, only RBC were used whereas only 7,3% of the GIB didn't require RBC transfusion. Patients requiring FC and/or PCC, needed more allogenic components. We observed, in accordance with the latest clinical practice guidelines and the published literature, a restrictive transfusion approach in our clinical practice. |
format | Online Article Text |
id | pubmed-9749046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-97490462022-12-15 Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis Costa, Ana Palricas Pereira, Carla Leal Garção, Ana Rodrigues, Anabela Clin Appl Thromb Hemost Original Manuscript Acute upper or lower Gastrointestinal bleeding (GIB) is a clinical emergency in which transfusion can be lifesaving. An individualized and restrictive transfusion strategy is recommended. This study aims to analyze and evaluate GIB transfusion practices during one year in a large tertiary hospital in Lisbon, Portugal. All patients with GIB and transfusion support during 2014 were identified and clinical data collected and statistically treated. There were 1005 GIB transfusion episodes, in a total of 494 patients. Upper GIB was more common. The median haemoglobin concentration that triggered RBC transfusion was 7,6 g/dL with a median of 2 RBC per episode. In 21,9% of episodes, RBC were used in combination with other therapies, in 70,8%, only RBC were administered and in 7,3% RBC were not used at all. In the subgroup of patients receiving FC and/or PCC there were higher median of blood products transfused: RBC (3 17 units), FFP (3 units), PC (1 unit). In a large percentage of the transfusion episodes for GIB, only RBC were used whereas only 7,3% of the GIB didn't require RBC transfusion. Patients requiring FC and/or PCC, needed more allogenic components. We observed, in accordance with the latest clinical practice guidelines and the published literature, a restrictive transfusion approach in our clinical practice. SAGE Publications 2022-12-12 /pmc/articles/PMC9749046/ /pubmed/36503291 http://dx.doi.org/10.1177/10760296221087219 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Manuscript Costa, Ana Palricas Pereira, Carla Leal Garção, Ana Rodrigues, Anabela Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title | Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title_full | Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title_fullStr | Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title_full_unstemmed | Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title_short | Transfusion Practices in Gastrointestinal Bleeding – a Tertiary Care Single-Centre Analysis |
title_sort | transfusion practices in gastrointestinal bleeding – a tertiary care single-centre analysis |
topic | Original Manuscript |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749046/ https://www.ncbi.nlm.nih.gov/pubmed/36503291 http://dx.doi.org/10.1177/10760296221087219 |
work_keys_str_mv | AT costaanapalricas transfusionpracticesingastrointestinalbleedingatertiarycaresinglecentreanalysis AT pereiracarlaleal transfusionpracticesingastrointestinalbleedingatertiarycaresinglecentreanalysis AT garcaoana transfusionpracticesingastrointestinalbleedingatertiarycaresinglecentreanalysis AT rodriguesanabela transfusionpracticesingastrointestinalbleedingatertiarycaresinglecentreanalysis |