Thrombus-specific/responsive biomimetic nanomedicine for spatiotemporal thrombolysis and alleviation of myocardial ischemia/reperfusion injury

Acute myocardial infarction (AMI) is usually caused by coronary thrombosis. However, the short half-life, lack of targetability and inevitable ischemia/reperfusion injury secondary to revascularization, which characterizes tissue plasminogen activator (tPA) limit its thrombolytic efficacy for AMI. T...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoyu, Hong, Ting, Zang, Jie, Shao, Rongjiao, Hou, Xumin, Wang, Kai, Liu, Weizhuo, Su, Fan, He, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749152/
https://www.ncbi.nlm.nih.gov/pubmed/36514154
http://dx.doi.org/10.1186/s12951-022-01686-1

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