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Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS)
BACKGROUND: Fall is a major cause of mortality and cause a significant burden on the healthcare system and economic system. Weak grip strength signifies impaired function. Older people with weak grip strength are at a higher risk of death. China has the largest ageing population in the world today....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749312/ https://www.ncbi.nlm.nih.gov/pubmed/36514090 http://dx.doi.org/10.1186/s12889-022-14753-x |
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author | Liu, Hao Hou, Yunfei Li, Hu Lin, Jianhao |
author_facet | Liu, Hao Hou, Yunfei Li, Hu Lin, Jianhao |
author_sort | Liu, Hao |
collection | PubMed |
description | BACKGROUND: Fall is a major cause of mortality and cause a significant burden on the healthcare system and economic system. Weak grip strength signifies impaired function. Older people with weak grip strength are at a higher risk of death. China has the largest ageing population in the world today. This study aims to analyze the factors contributing to weak grip strength and fall among Chinese. METHODS: This study analyzed data from the 2011 baseline and 2015 follow-up survey of the China Health and Retirement Longitudinal Study (CHARLS). To identify the risk factors of fall and weak grip strength, we used a stepwise multivariable logistic regression model and a least absolute shrinkage and selection operator (LASSO) regression model. RESULTS: In the LASSO regression model, all the risk factors were not shrunken. In the stepwise logistic regression model, adjusted for gender, age, grip strength, depression, and chronic disease, we found that female (aOR = 1.376, 95% CI = 1.243–1.523; P < 0.001), history of ischemic stroke (aOR = 1.786, 95% CI = 1.263–2.524; P = 0.001), depression (aOR = 1.559, 95% CI = 1.396–1.742; P < 0.001), weak grip strength (aOR = 1.285, 95% CI = 1.105–1.494; P = 0.001), older age (aOR = 1.227, 95% CI = 1.163–1.294; P < 0.001), rheumatoid arthritis (aOR = 1.410, 95% CI = 1.270–1.560; P < 0.001), history of kidney disease (aOR = 1.383, 95% CI = 1.136–1.682; P = 0.001) were factors associated with fall significantly. After further adjusting, we found the risk factors of weak grip strength included symptomatic knee osteoarthritis (aOR = 1.755, 95% CI 1.158–2.661; P = 0.008), living in rural area (aOR = 2.056, 95% CI 1.290–3.277; P = 0.002), depression (aOR = 1.523, 95% CI 1.116–2.078; P = 0.008), older age (aOR = 2.116, 95% CI 1.801–2.486; P < 0.001). CONCLUSION: From the study, we found that older age and depression were risk factors of weak grip strength and fall. Weak grip strength was a risk factor of fall. Female, ischemic stroke, kidney disease, rheumatoid arthritis were risk factors of fall; living in rural area and symptomatic knee osteoarthritis were risk factors of weak grip strength. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-14753-x. |
format | Online Article Text |
id | pubmed-9749312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97493122022-12-15 Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) Liu, Hao Hou, Yunfei Li, Hu Lin, Jianhao BMC Public Health Research BACKGROUND: Fall is a major cause of mortality and cause a significant burden on the healthcare system and economic system. Weak grip strength signifies impaired function. Older people with weak grip strength are at a higher risk of death. China has the largest ageing population in the world today. This study aims to analyze the factors contributing to weak grip strength and fall among Chinese. METHODS: This study analyzed data from the 2011 baseline and 2015 follow-up survey of the China Health and Retirement Longitudinal Study (CHARLS). To identify the risk factors of fall and weak grip strength, we used a stepwise multivariable logistic regression model and a least absolute shrinkage and selection operator (LASSO) regression model. RESULTS: In the LASSO regression model, all the risk factors were not shrunken. In the stepwise logistic regression model, adjusted for gender, age, grip strength, depression, and chronic disease, we found that female (aOR = 1.376, 95% CI = 1.243–1.523; P < 0.001), history of ischemic stroke (aOR = 1.786, 95% CI = 1.263–2.524; P = 0.001), depression (aOR = 1.559, 95% CI = 1.396–1.742; P < 0.001), weak grip strength (aOR = 1.285, 95% CI = 1.105–1.494; P = 0.001), older age (aOR = 1.227, 95% CI = 1.163–1.294; P < 0.001), rheumatoid arthritis (aOR = 1.410, 95% CI = 1.270–1.560; P < 0.001), history of kidney disease (aOR = 1.383, 95% CI = 1.136–1.682; P = 0.001) were factors associated with fall significantly. After further adjusting, we found the risk factors of weak grip strength included symptomatic knee osteoarthritis (aOR = 1.755, 95% CI 1.158–2.661; P = 0.008), living in rural area (aOR = 2.056, 95% CI 1.290–3.277; P = 0.002), depression (aOR = 1.523, 95% CI 1.116–2.078; P = 0.008), older age (aOR = 2.116, 95% CI 1.801–2.486; P < 0.001). CONCLUSION: From the study, we found that older age and depression were risk factors of weak grip strength and fall. Weak grip strength was a risk factor of fall. Female, ischemic stroke, kidney disease, rheumatoid arthritis were risk factors of fall; living in rural area and symptomatic knee osteoarthritis were risk factors of weak grip strength. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-022-14753-x. BioMed Central 2022-12-13 /pmc/articles/PMC9749312/ /pubmed/36514090 http://dx.doi.org/10.1186/s12889-022-14753-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Liu, Hao Hou, Yunfei Li, Hu Lin, Jianhao Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title | Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title_full | Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title_fullStr | Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title_full_unstemmed | Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title_short | Influencing factors of weak grip strength and fall: a study based on the China Health and Retirement Longitudinal Study (CHARLS) |
title_sort | influencing factors of weak grip strength and fall: a study based on the china health and retirement longitudinal study (charls) |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749312/ https://www.ncbi.nlm.nih.gov/pubmed/36514090 http://dx.doi.org/10.1186/s12889-022-14753-x |
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