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Buprenorphine in rats: potent analgesic or trigger for fatal side effects?

With ongoing animal welfare efforts, multimodal analgesia is often recommended to implement in study protocols. Buprenorphine with very potent analgesic effect is a standard opioid for the use in this context in rats. In this study, two rat strains (LEW/NHanZtm, n = 6 and Crl:CD(SD), n = 8) underwen...

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Detalles Bibliográficos
Autores principales:	Reifenrath, Janin, Heider, Miriam, Kempfert, Merle, Harting, Heidi, Weidemann, Friederike, Strauss, Sarah, Angrisani, Nina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749369/ https://www.ncbi.nlm.nih.gov/pubmed/36514178 http://dx.doi.org/10.1186/s13028-022-00661-y

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