SARS-CoV-2 RdRp uses NDPs as a substrate and is able to incorporate NHC into RNA from diphosphate form molnupiravir

The coronavirus disease 2019 has been ravaging throughout the world for three years and has severely impaired both human health and the economy. The causative agent, severe acute respiratory syndrome coronavirus 2 employs the viral RNA dependent RNA polymerase (RdRp) complex for genome replication a...

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Detalles Bibliográficos
Autores principales: Wang, Maofeng, Wu, Cancan, Liu, Nan, Zhang, Fengyu, Dong, Hongjie, Wang, Shuai, Chen, Min, Jiang, Xiaoqiong, Zhang, Kundi, Gu, Lichuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749393/
https://www.ncbi.nlm.nih.gov/pubmed/36528144
http://dx.doi.org/10.1016/j.ijbiomac.2022.12.112

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