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Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects

This research work focuses on the fabrication and study of a series of nanocomposites consisting of two types of hydroxyapatite (HA), obtained by precipitate (HAP) and sol–gel (HAG) methods, and a boro-silico-phosphate bioglass. The microstructure and chemical, mechanical, and biological properties...

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Autores principales: Shikimaka, Olga, Bivol, Mihaela, Sava, Bogdan A, Dumitru, Marius, Tardei, Christu, Sbarcea, Beatrice G, Grabco, Daria, Pyrtsac, Constantin, Topal, Daria, Prisacaru, Andrian, Cobzac, Vitalie, Nacu, Viorel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749502/
https://www.ncbi.nlm.nih.gov/pubmed/36570613
http://dx.doi.org/10.3762/bjnano.13.123
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author Shikimaka, Olga
Bivol, Mihaela
Sava, Bogdan A
Dumitru, Marius
Tardei, Christu
Sbarcea, Beatrice G
Grabco, Daria
Pyrtsac, Constantin
Topal, Daria
Prisacaru, Andrian
Cobzac, Vitalie
Nacu, Viorel
author_facet Shikimaka, Olga
Bivol, Mihaela
Sava, Bogdan A
Dumitru, Marius
Tardei, Christu
Sbarcea, Beatrice G
Grabco, Daria
Pyrtsac, Constantin
Topal, Daria
Prisacaru, Andrian
Cobzac, Vitalie
Nacu, Viorel
author_sort Shikimaka, Olga
collection PubMed
description This research work focuses on the fabrication and study of a series of nanocomposites consisting of two types of hydroxyapatite (HA), obtained by precipitate (HAP) and sol–gel (HAG) methods, and a boro-silico-phosphate bioglass. The microstructure and chemical, mechanical, and biological properties as functions of three factors, namely (i) the type of hydroxyapatite, (ii) glass content, and (iii) sintering temperature, were investigated. It was found that all of these factors affect the final composition and microstructure, especially, porosity, which shows significantly lower values for HAP-based composites than for HAG-based ones and higher values for higher glass content. This, in turn, has an impact on the microhardness, which exhibits a strong correlation with porosity, as well as on the mineralization capability and cell viability due to the different dissolution rate.
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spelling pubmed-97495022022-12-23 Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects Shikimaka, Olga Bivol, Mihaela Sava, Bogdan A Dumitru, Marius Tardei, Christu Sbarcea, Beatrice G Grabco, Daria Pyrtsac, Constantin Topal, Daria Prisacaru, Andrian Cobzac, Vitalie Nacu, Viorel Beilstein J Nanotechnol Full Research Paper This research work focuses on the fabrication and study of a series of nanocomposites consisting of two types of hydroxyapatite (HA), obtained by precipitate (HAP) and sol–gel (HAG) methods, and a boro-silico-phosphate bioglass. The microstructure and chemical, mechanical, and biological properties as functions of three factors, namely (i) the type of hydroxyapatite, (ii) glass content, and (iii) sintering temperature, were investigated. It was found that all of these factors affect the final composition and microstructure, especially, porosity, which shows significantly lower values for HAP-based composites than for HAG-based ones and higher values for higher glass content. This, in turn, has an impact on the microhardness, which exhibits a strong correlation with porosity, as well as on the mineralization capability and cell viability due to the different dissolution rate. Beilstein-Institut 2022-12-12 /pmc/articles/PMC9749502/ /pubmed/36570613 http://dx.doi.org/10.3762/bjnano.13.123 Text en Copyright © 2022, Shikimaka et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjnano/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Full Research Paper
Shikimaka, Olga
Bivol, Mihaela
Sava, Bogdan A
Dumitru, Marius
Tardei, Christu
Sbarcea, Beatrice G
Grabco, Daria
Pyrtsac, Constantin
Topal, Daria
Prisacaru, Andrian
Cobzac, Vitalie
Nacu, Viorel
Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title_full Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title_fullStr Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title_full_unstemmed Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title_short Hydroxyapatite–bioglass nanocomposites: Structural, mechanical, and biological aspects
title_sort hydroxyapatite–bioglass nanocomposites: structural, mechanical, and biological aspects
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749502/
https://www.ncbi.nlm.nih.gov/pubmed/36570613
http://dx.doi.org/10.3762/bjnano.13.123
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