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Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis

Risk of death from undernutrition is thought to be higher in younger than in older children, but evidence is mixed. Research also demonstrates sex differences whereby boys have a higher prevalence of undernutrition than girls. This analysis described mortality risk associated with anthropometric def...

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Autores principales: Thurstans, Susan, Wrottesley, Stephanie V., Fenn, Bridget, Khara, Tanya, Bahwere, Paluku, Berkley, James A., Black, Robert E., Boyd, Erin, Garenne, Michel, Isanaka, Sheila, Lelijveld, Natasha, McDonald, Christine M., Mertens, Andrew, Mwangome, Martha, O'Brien, Kieran S., Stobaugh, Heather, Taneja, Sunita, West, Keith P., Guerrero, Saul, Kerac, Marko, Briend, André, Myatt, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749608/
https://www.ncbi.nlm.nih.gov/pubmed/36164997
http://dx.doi.org/10.1111/mcn.13431
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author Thurstans, Susan
Wrottesley, Stephanie V.
Fenn, Bridget
Khara, Tanya
Bahwere, Paluku
Berkley, James A.
Black, Robert E.
Boyd, Erin
Garenne, Michel
Isanaka, Sheila
Lelijveld, Natasha
McDonald, Christine M.
Mertens, Andrew
Mwangome, Martha
O'Brien, Kieran S.
Stobaugh, Heather
Taneja, Sunita
West, Keith P.
Guerrero, Saul
Kerac, Marko
Briend, André
Myatt, Mark
author_facet Thurstans, Susan
Wrottesley, Stephanie V.
Fenn, Bridget
Khara, Tanya
Bahwere, Paluku
Berkley, James A.
Black, Robert E.
Boyd, Erin
Garenne, Michel
Isanaka, Sheila
Lelijveld, Natasha
McDonald, Christine M.
Mertens, Andrew
Mwangome, Martha
O'Brien, Kieran S.
Stobaugh, Heather
Taneja, Sunita
West, Keith P.
Guerrero, Saul
Kerac, Marko
Briend, André
Myatt, Mark
author_sort Thurstans, Susan
collection PubMed
description Risk of death from undernutrition is thought to be higher in younger than in older children, but evidence is mixed. Research also demonstrates sex differences whereby boys have a higher prevalence of undernutrition than girls. This analysis described mortality risk associated with anthropometric deficits (wasting, underweight and stunting) in children 6–59 months by age and sex. We categorised children into younger (6–23 months) and older (24–59 months) age groups. Age and sex variations in near‐term (within 6 months) mortality risk, associated with individual anthropometric deficits were assessed in a secondary analysis of multi‐country cohort data. A random effects meta‐analysis was performed. Data from seven low‐or‐middle‐income‐countries collected between 1977 and 2013 were analysed. One thousand twenty deaths were recorded for children with anthropometric deficits. Pooled meta‐analysis estimates showed no differences by age in absolute mortality risk for wasting (RR 1.08, p = 0.826 for MUAC < 125 mm; RR 1.35, p = 0.272 for WHZ < −2). For underweight and stunting, absolute risk of death was higher in younger (RR 2.57, p < 0.001) compared with older children (RR 2.83, p < 0.001). For all deficits, there were no differences in mortality risk for girls compared with boys. There were no differences in the risk of mortality between younger and older wasted children, supporting continued inclusion of all children under‐five in wasting treatment programmes. The risk of mortality associated with underweight and stunting was higher among younger children, suggesting that prevention programmes might be justified in focusing on younger children where resources are limited. There were no sex differences by age in mortality risk for all deficits.
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spelling pubmed-97496082022-12-15 Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis Thurstans, Susan Wrottesley, Stephanie V. Fenn, Bridget Khara, Tanya Bahwere, Paluku Berkley, James A. Black, Robert E. Boyd, Erin Garenne, Michel Isanaka, Sheila Lelijveld, Natasha McDonald, Christine M. Mertens, Andrew Mwangome, Martha O'Brien, Kieran S. Stobaugh, Heather Taneja, Sunita West, Keith P. Guerrero, Saul Kerac, Marko Briend, André Myatt, Mark Matern Child Nutr Original Articles Risk of death from undernutrition is thought to be higher in younger than in older children, but evidence is mixed. Research also demonstrates sex differences whereby boys have a higher prevalence of undernutrition than girls. This analysis described mortality risk associated with anthropometric deficits (wasting, underweight and stunting) in children 6–59 months by age and sex. We categorised children into younger (6–23 months) and older (24–59 months) age groups. Age and sex variations in near‐term (within 6 months) mortality risk, associated with individual anthropometric deficits were assessed in a secondary analysis of multi‐country cohort data. A random effects meta‐analysis was performed. Data from seven low‐or‐middle‐income‐countries collected between 1977 and 2013 were analysed. One thousand twenty deaths were recorded for children with anthropometric deficits. Pooled meta‐analysis estimates showed no differences by age in absolute mortality risk for wasting (RR 1.08, p = 0.826 for MUAC < 125 mm; RR 1.35, p = 0.272 for WHZ < −2). For underweight and stunting, absolute risk of death was higher in younger (RR 2.57, p < 0.001) compared with older children (RR 2.83, p < 0.001). For all deficits, there were no differences in mortality risk for girls compared with boys. There were no differences in the risk of mortality between younger and older wasted children, supporting continued inclusion of all children under‐five in wasting treatment programmes. The risk of mortality associated with underweight and stunting was higher among younger children, suggesting that prevention programmes might be justified in focusing on younger children where resources are limited. There were no sex differences by age in mortality risk for all deficits. John Wiley and Sons Inc. 2022-09-27 /pmc/articles/PMC9749608/ /pubmed/36164997 http://dx.doi.org/10.1111/mcn.13431 Text en © 2022 The Authors. Maternal & Child Nutrition published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Thurstans, Susan
Wrottesley, Stephanie V.
Fenn, Bridget
Khara, Tanya
Bahwere, Paluku
Berkley, James A.
Black, Robert E.
Boyd, Erin
Garenne, Michel
Isanaka, Sheila
Lelijveld, Natasha
McDonald, Christine M.
Mertens, Andrew
Mwangome, Martha
O'Brien, Kieran S.
Stobaugh, Heather
Taneja, Sunita
West, Keith P.
Guerrero, Saul
Kerac, Marko
Briend, André
Myatt, Mark
Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title_full Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title_fullStr Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title_full_unstemmed Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title_short Anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: A meta‐analysis
title_sort anthropometric deficits and the associated risk of death by age and sex in children aged 6–59 months: a meta‐analysis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749608/
https://www.ncbi.nlm.nih.gov/pubmed/36164997
http://dx.doi.org/10.1111/mcn.13431
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