Cargando…

Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort

BACKGROUND: Cardiovascular disease (CVD) has a disproportionate effect on mortality among the poorest people. We assessed the impact on CVD and all-cause mortality of the world's largest conditional cash transfer, Brazil’s Bolsa Família Programme (BFP). METHODS: We linked administrative data fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pescarini, Julia M, Campbell, Desmond, Amorim, Leila D, Falcão, Ila R, Ferreira, Andrêa J F, Allik, Mirjam, Shaw, Richard J, Malta, Deborah C, Ali, M Sanni, Smeeth, Liam, Barreto, Mauricio L, Leyland, Alastair, Craig, Peter, Aquino, Estela M L, Katikireddi, Srinivasa Vittal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749722/
https://www.ncbi.nlm.nih.gov/pubmed/36172959
http://dx.doi.org/10.1093/ije/dyac188
_version_ 1784850101705900032
author Pescarini, Julia M
Campbell, Desmond
Amorim, Leila D
Falcão, Ila R
Ferreira, Andrêa J F
Allik, Mirjam
Shaw, Richard J
Malta, Deborah C
Ali, M Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair
Craig, Peter
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
author_facet Pescarini, Julia M
Campbell, Desmond
Amorim, Leila D
Falcão, Ila R
Ferreira, Andrêa J F
Allik, Mirjam
Shaw, Richard J
Malta, Deborah C
Ali, M Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair
Craig, Peter
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
author_sort Pescarini, Julia M
collection PubMed
description BACKGROUND: Cardiovascular disease (CVD) has a disproportionate effect on mortality among the poorest people. We assessed the impact on CVD and all-cause mortality of the world's largest conditional cash transfer, Brazil’s Bolsa Família Programme (BFP). METHODS: We linked administrative data from the 100 Million Brazilian Cohort with BFP receipt and national mortality data. We followed individuals who applied for BFP between 1 January 2011 and 31 December 2015, until 31 December 2015. We used marginal structural models to estimate the effect of BFP on all-age and premature (30–69 years) CVD and all-cause mortality. We conducted stratified analyses by levels of material deprivation and access to healthcare. We checked the robustness of our findings by restricting the analysis to municipalities with better mortality data and by using alternative statistical methods. RESULTS: We studied 17 981 582 individuals, of whom 4 855 324 were aged 30–69 years. Three-quarters (76.2%) received BFP, with a mean follow-up post-award of 2.6 years. We detected 106 807 deaths by all causes, of which 60 893 were premature; and 23 389 CVD deaths, of which 15 292 were premature. BFP was associated with reductions in premature all-cause mortality [hazard ratio (HR) = 0.96, 95% CI = 0.94–0.98], premature CVD (HR = 0.96, 95% CI = 0.92–1.00) and all-age CVD (HR = 0.96, 95% CI = 0.93–1.00) but not all-age all-cause mortality (HR = 1.00, 95% CI = 0.98–1.02). In stratified and robustness analyses, BFP was consistently associated with mortality reductions for individuals living in the two most deprived quintiles. CONCLUSIONS: BFP appears to have a small to null effect on premature CVD and all-cause mortality in the short term; the long-term impact remains unknown.
format Online
Article
Text
id pubmed-9749722
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-97497222022-12-15 Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort Pescarini, Julia M Campbell, Desmond Amorim, Leila D Falcão, Ila R Ferreira, Andrêa J F Allik, Mirjam Shaw, Richard J Malta, Deborah C Ali, M Sanni Smeeth, Liam Barreto, Mauricio L Leyland, Alastair Craig, Peter Aquino, Estela M L Katikireddi, Srinivasa Vittal Int J Epidemiol Cardiovascular Risk Factors BACKGROUND: Cardiovascular disease (CVD) has a disproportionate effect on mortality among the poorest people. We assessed the impact on CVD and all-cause mortality of the world's largest conditional cash transfer, Brazil’s Bolsa Família Programme (BFP). METHODS: We linked administrative data from the 100 Million Brazilian Cohort with BFP receipt and national mortality data. We followed individuals who applied for BFP between 1 January 2011 and 31 December 2015, until 31 December 2015. We used marginal structural models to estimate the effect of BFP on all-age and premature (30–69 years) CVD and all-cause mortality. We conducted stratified analyses by levels of material deprivation and access to healthcare. We checked the robustness of our findings by restricting the analysis to municipalities with better mortality data and by using alternative statistical methods. RESULTS: We studied 17 981 582 individuals, of whom 4 855 324 were aged 30–69 years. Three-quarters (76.2%) received BFP, with a mean follow-up post-award of 2.6 years. We detected 106 807 deaths by all causes, of which 60 893 were premature; and 23 389 CVD deaths, of which 15 292 were premature. BFP was associated with reductions in premature all-cause mortality [hazard ratio (HR) = 0.96, 95% CI = 0.94–0.98], premature CVD (HR = 0.96, 95% CI = 0.92–1.00) and all-age CVD (HR = 0.96, 95% CI = 0.93–1.00) but not all-age all-cause mortality (HR = 1.00, 95% CI = 0.98–1.02). In stratified and robustness analyses, BFP was consistently associated with mortality reductions for individuals living in the two most deprived quintiles. CONCLUSIONS: BFP appears to have a small to null effect on premature CVD and all-cause mortality in the short term; the long-term impact remains unknown. Oxford University Press 2022-09-28 /pmc/articles/PMC9749722/ /pubmed/36172959 http://dx.doi.org/10.1093/ije/dyac188 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the International Epidemiological Association. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Risk Factors
Pescarini, Julia M
Campbell, Desmond
Amorim, Leila D
Falcão, Ila R
Ferreira, Andrêa J F
Allik, Mirjam
Shaw, Richard J
Malta, Deborah C
Ali, M Sanni
Smeeth, Liam
Barreto, Mauricio L
Leyland, Alastair
Craig, Peter
Aquino, Estela M L
Katikireddi, Srinivasa Vittal
Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title_full Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title_fullStr Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title_full_unstemmed Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title_short Impact of Brazil’s Bolsa Família Programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 Million Brazilian Cohort
title_sort impact of brazil’s bolsa família programme on cardiovascular and all-cause mortality: a natural experiment study using the 100 million brazilian cohort
topic Cardiovascular Risk Factors
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749722/
https://www.ncbi.nlm.nih.gov/pubmed/36172959
http://dx.doi.org/10.1093/ije/dyac188
work_keys_str_mv AT pescarinijuliam impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT campbelldesmond impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT amorimleilad impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT falcaoilar impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT ferreiraandreajf impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT allikmirjam impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT shawrichardj impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT maltadeborahc impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT alimsanni impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT smeethliam impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT barretomauriciol impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT leylandalastair impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT craigpeter impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT aquinoestelaml impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort
AT katikireddisrinivasavittal impactofbrazilsbolsafamiliaprogrammeoncardiovascularandallcausemortalityanaturalexperimentstudyusingthe100millionbraziliancohort