Co-targeting triple-negative breast cancer cells and endothelial cells by metronomic chemotherapy inhibits cell regrowth and migration via downregulation of the FAK/VEGFR2/VEGF axis and autophagy/apoptosis activation

High-dose standard-of-care chemotherapy is the only option for triple-negative breast cancer (TNBC) patients, which eventually die due to metastatic tumors. Recently, metronomic chemotherapy (mCHT) showed advantages in treating TNBCs leading us to investigate the anti-metastatic and anti-angiogenic...

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Detalles Bibliográficos
Autores principales: Scagliotti, Arianna, Capizzi, Laura, Cazzaniga, Marina Elena, Ilari, Alice, De Giorgi, Marco, Cordani, Nicoletta, Gallazzi, Matteo, Bruno, Antonino, Pelosi, Giuseppe, Albini, Adriana, Lavitrano, Marialuisa, Grassilli, Emanuela, Cerrito, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749857/
https://www.ncbi.nlm.nih.gov/pubmed/36531071
http://dx.doi.org/10.3389/fonc.2022.998274

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