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Changes in adenosine receptors and neurotrophic factors in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis: Modulation by chronic caffeine

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of corticospinal tract motor neurons. Previous studies showed that adenosine-mediated neuromodulation is disturbed in ALS and that vascular endothelial growth factor (VEGF) has a neuroprotective function in ALS mous...

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Detalles Bibliográficos
Autores principales: Rei, Nádia, Valente, Cláudia A., Vaz, Sandra H., Farinha-Ferreira, Miguel, Ribeiro, Joaquim A., Sebastião, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9749988/
https://www.ncbi.nlm.nih.gov/pubmed/36516126
http://dx.doi.org/10.1371/journal.pone.0272104