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Multivalent state transitions shape the intratumoral composition of small cell lung carcinoma

Studies to date have not resolved how diverse transcriptional programs contribute to the intratumoral heterogeneity of small cell lung carcinoma (SCLC), an aggressive tumor associated with a dismal prognosis. Here, we identify distinct and commutable transcriptional states that confer discrete funct...

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Detalles Bibliográficos
Autores principales:	Gopal, Priyanka, Petty, Aaron, Rogacki, Kevin, Bera, Titas, Bareja, Rohan, Peacock, Craig D., Abazeed, Mohamed E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750150/ https://www.ncbi.nlm.nih.gov/pubmed/36516249 http://dx.doi.org/10.1126/sciadv.abp8674

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