Mechanistic insight into female predominance in Alzheimer’s disease based on aberrant protein S-nitrosylation of C3

Protein S-nitros(yl)ation (SNO) is a posttranslational modification involved in diverse processes in health and disease and can contribute to synaptic damage in Alzheimer’s disease (AD). To identify SNO proteins in AD brains, we used triaryl phosphine (SNOTRAP) combined with mass spectrometry (MS)....

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Detalles Bibliográficos
Autores principales: Yang, Hongmei, Oh, Chang-ki, Amal, Haitham, Wishnok, John S., Lewis, Sarah, Schahrer, Emily, Trudler, Dorit, Nakamura, Tomohiro, Tannenbaum, Steven R., Lipton, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750152/
https://www.ncbi.nlm.nih.gov/pubmed/36516243
http://dx.doi.org/10.1126/sciadv.ade0764

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