Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees

In contrast to a second dose of the SARS-CoV-2 mRNA vaccine, a third dose elicits potent neutralizing activity against the Omicron variant. To address the underlying mechanism for this differential antibody response, we examined spike receptor-binding domain (RBD)–specific memory B cells in vaccinat...

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Detalles Bibliográficos
Autores principales: Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Yamamoto, Hiromi, Sakakibara, Shuhei, Ono, Chikako, Itoh, Yumi, Terooatea, Tommy, Yamashita, Kazuo, Okamoto, Toru, Hashii, Noritaka, Ishii-Watabe, Akiko, Butler, Noah S., Matsuura, Yoshiharu, Matsumoto, Hisatake, Otsuka, Shinya, Hiraoka, Kei, Teshima, Takanori, Murakami, Masaaki, Kurosaki, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750191/
https://www.ncbi.nlm.nih.gov/pubmed/36512034
http://dx.doi.org/10.1084/jem.20221786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750191/
https://www.ncbi.nlm.nih.gov/pubmed/36512034
http://dx.doi.org/10.1084/jem.20221786

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