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Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees
In contrast to a second dose of the SARS-CoV-2 mRNA vaccine, a third dose elicits potent neutralizing activity against the Omicron variant. To address the underlying mechanism for this differential antibody response, we examined spike receptor-binding domain (RBD)–specific memory B cells in vaccinat...
Autores principales: | Inoue, Takeshi, Shinnakasu, Ryo, Kawai, Chie, Yamamoto, Hiromi, Sakakibara, Shuhei, Ono, Chikako, Itoh, Yumi, Terooatea, Tommy, Yamashita, Kazuo, Okamoto, Toru, Hashii, Noritaka, Ishii-Watabe, Akiko, Butler, Noah S., Matsuura, Yoshiharu, Matsumoto, Hisatake, Otsuka, Shinya, Hiraoka, Kei, Teshima, Takanori, Murakami, Masaaki, Kurosaki, Tomohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750191/ https://www.ncbi.nlm.nih.gov/pubmed/36512034 http://dx.doi.org/10.1084/jem.20221786 |
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