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Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by neurodegeneration, nerve loss, neurofibrillary tangles, and Aβ plaques. In modern medical science, there has been a serious obstacle to the effective treatment of AD. At present, there is no clinically proven and effective wes...

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Autores principales: Liu, Zhao, Guan, Ruiqian, Bu, Fan, Pan, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750551/
https://www.ncbi.nlm.nih.gov/pubmed/36626477
http://dx.doi.org/10.1097/MD.0000000000032218
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author Liu, Zhao
Guan, Ruiqian
Bu, Fan
Pan, Limin
author_facet Liu, Zhao
Guan, Ruiqian
Bu, Fan
Pan, Limin
author_sort Liu, Zhao
collection PubMed
description Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by neurodegeneration, nerve loss, neurofibrillary tangles, and Aβ plaques. In modern medical science, there has been a serious obstacle to the effective treatment of AD. At present, there is no clinically proven and effective western medicine treatment for AD. The reason is that the etiology of AD is not yet fully understood. In 2018, the international community put forward a purely biological definition of AD, but soon this view of biomarkers was widely questioned, because the so-called AD biomarkers are shared with other neurological diseases, the diagnostic accuracy is low, and they face various challenges in the process of clinical diagnosis and treatment. Nowadays, scholars increasingly regard AD as the result of multimechanism and multicenter interaction. Because there is no exact Western medicine treatment for AD, the times call for the comprehensive treatment of AD in traditional Chinese medicine (TCM). AD belongs to the category of “dull disease” in TCM. For thousands of years, TCM has accumulated a lot of relevant treatment experience in the process of diagnosis and treatment. TCM, acupuncture, and the combination of acupuncture and medicine all play an important role in the treatment of AD. Based on the research progress of modern medicine on the pathophysiology of AD, this paper discusses the treatment of this disease with the combination of acupuncture and medicine.
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spelling pubmed-97505512022-12-28 Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review Liu, Zhao Guan, Ruiqian Bu, Fan Pan, Limin Medicine (Baltimore) 5300 Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by neurodegeneration, nerve loss, neurofibrillary tangles, and Aβ plaques. In modern medical science, there has been a serious obstacle to the effective treatment of AD. At present, there is no clinically proven and effective western medicine treatment for AD. The reason is that the etiology of AD is not yet fully understood. In 2018, the international community put forward a purely biological definition of AD, but soon this view of biomarkers was widely questioned, because the so-called AD biomarkers are shared with other neurological diseases, the diagnostic accuracy is low, and they face various challenges in the process of clinical diagnosis and treatment. Nowadays, scholars increasingly regard AD as the result of multimechanism and multicenter interaction. Because there is no exact Western medicine treatment for AD, the times call for the comprehensive treatment of AD in traditional Chinese medicine (TCM). AD belongs to the category of “dull disease” in TCM. For thousands of years, TCM has accumulated a lot of relevant treatment experience in the process of diagnosis and treatment. TCM, acupuncture, and the combination of acupuncture and medicine all play an important role in the treatment of AD. Based on the research progress of modern medicine on the pathophysiology of AD, this paper discusses the treatment of this disease with the combination of acupuncture and medicine. Lippincott Williams & Wilkins 2022-12-09 /pmc/articles/PMC9750551/ /pubmed/36626477 http://dx.doi.org/10.1097/MD.0000000000032218 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 5300
Liu, Zhao
Guan, Ruiqian
Bu, Fan
Pan, Limin
Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title_full Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title_fullStr Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title_full_unstemmed Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title_short Treatment of Alzheimer’s disease by combination of acupuncture and Chinese medicine based on pathophysiological mechanism: A review
title_sort treatment of alzheimer’s disease by combination of acupuncture and chinese medicine based on pathophysiological mechanism: a review
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750551/
https://www.ncbi.nlm.nih.gov/pubmed/36626477
http://dx.doi.org/10.1097/MD.0000000000032218
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