Cargando…

An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review

Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reportin...

Descripción completa

Detalles Bibliográficos
Autores principales: Meshref, Mostafa, Shaheen, Nour, Swed, Sarya, Ibrahim, Mohamed, Mostafa, Mostafa Reda, Algazar, Mohamed Osman, Dobs, Monica, Elsayed, Sarah Ibrahim, Amro, Yara, Afsa, Ahmed, Morra, Mostafa Ebraheem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750665/
https://www.ncbi.nlm.nih.gov/pubmed/36626529
http://dx.doi.org/10.1097/MD.0000000000032023
_version_ 1784850305990524928
author Meshref, Mostafa
Shaheen, Nour
Swed, Sarya
Ibrahim, Mohamed
Mostafa, Mostafa Reda
Algazar, Mohamed Osman
Dobs, Monica
Elsayed, Sarah Ibrahim
Amro, Yara
Afsa, Ahmed
Morra, Mostafa Ebraheem
author_facet Meshref, Mostafa
Shaheen, Nour
Swed, Sarya
Ibrahim, Mohamed
Mostafa, Mostafa Reda
Algazar, Mohamed Osman
Dobs, Monica
Elsayed, Sarah Ibrahim
Amro, Yara
Afsa, Ahmed
Morra, Mostafa Ebraheem
author_sort Meshref, Mostafa
collection PubMed
description Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reporting a 55-year-old male patient with unilateral diplopia considering it as a case of multisystem inflammatory syndrome in adults. We also reviewed the literature systematically for the previously reported studies/cases with third, fourth and sixth cranial nerve palsies due to or after Covid-19. RESULTS: The literature search yielded 17 studies reporting 29 patients. 71.4% of the patients were males with a mean age of 42.23 years. Ophthalmological symptoms took 9.7 days to appear after the respiratory involvement. All patients had diplopia as part of their visual symptoms. 41.4% of the patients had unilateral sixth nerve palsy, 24% had bilateral sixth nerve involvement, 17% had fourth nerve involvement, and 27.6% had third nerve involvement. CONCLUSION: Ophthalmoplegia is considered presenting symptom of Covid-19. Further research is needed to detect all neuro-ophthalmological manifestations of Covid-19.
format Online
Article
Text
id pubmed-9750665
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-97506652022-12-28 An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review Meshref, Mostafa Shaheen, Nour Swed, Sarya Ibrahim, Mohamed Mostafa, Mostafa Reda Algazar, Mohamed Osman Dobs, Monica Elsayed, Sarah Ibrahim Amro, Yara Afsa, Ahmed Morra, Mostafa Ebraheem Medicine (Baltimore) 5300 Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reporting a 55-year-old male patient with unilateral diplopia considering it as a case of multisystem inflammatory syndrome in adults. We also reviewed the literature systematically for the previously reported studies/cases with third, fourth and sixth cranial nerve palsies due to or after Covid-19. RESULTS: The literature search yielded 17 studies reporting 29 patients. 71.4% of the patients were males with a mean age of 42.23 years. Ophthalmological symptoms took 9.7 days to appear after the respiratory involvement. All patients had diplopia as part of their visual symptoms. 41.4% of the patients had unilateral sixth nerve palsy, 24% had bilateral sixth nerve involvement, 17% had fourth nerve involvement, and 27.6% had third nerve involvement. CONCLUSION: Ophthalmoplegia is considered presenting symptom of Covid-19. Further research is needed to detect all neuro-ophthalmological manifestations of Covid-19. Lippincott Williams & Wilkins 2022-12-09 /pmc/articles/PMC9750665/ /pubmed/36626529 http://dx.doi.org/10.1097/MD.0000000000032023 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 5300
Meshref, Mostafa
Shaheen, Nour
Swed, Sarya
Ibrahim, Mohamed
Mostafa, Mostafa Reda
Algazar, Mohamed Osman
Dobs, Monica
Elsayed, Sarah Ibrahim
Amro, Yara
Afsa, Ahmed
Morra, Mostafa Ebraheem
An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title_full An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title_fullStr An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title_full_unstemmed An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title_short An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
title_sort overview of third, fourth and sixth cranial nerve palsies in the setting of covid-19: a case report and systematic review
topic 5300
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750665/
https://www.ncbi.nlm.nih.gov/pubmed/36626529
http://dx.doi.org/10.1097/MD.0000000000032023
work_keys_str_mv AT meshrefmostafa anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT shaheennour anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT swedsarya anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT ibrahimmohamed anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT mostafamostafareda anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT algazarmohamedosman anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT dobsmonica anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT elsayedsarahibrahim anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT amroyara anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT afsaahmed anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT morramostafaebraheem anoverviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT meshrefmostafa overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT shaheennour overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT swedsarya overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT ibrahimmohamed overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT mostafamostafareda overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT algazarmohamedosman overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT dobsmonica overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT elsayedsarahibrahim overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT amroyara overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT afsaahmed overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview
AT morramostafaebraheem overviewofthirdfourthandsixthcranialnervepalsiesinthesettingofcovid19acasereportandsystematicreview