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An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review
Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reportin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750665/ https://www.ncbi.nlm.nih.gov/pubmed/36626529 http://dx.doi.org/10.1097/MD.0000000000032023 |
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author | Meshref, Mostafa Shaheen, Nour Swed, Sarya Ibrahim, Mohamed Mostafa, Mostafa Reda Algazar, Mohamed Osman Dobs, Monica Elsayed, Sarah Ibrahim Amro, Yara Afsa, Ahmed Morra, Mostafa Ebraheem |
author_facet | Meshref, Mostafa Shaheen, Nour Swed, Sarya Ibrahim, Mohamed Mostafa, Mostafa Reda Algazar, Mohamed Osman Dobs, Monica Elsayed, Sarah Ibrahim Amro, Yara Afsa, Ahmed Morra, Mostafa Ebraheem |
author_sort | Meshref, Mostafa |
collection | PubMed |
description | Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reporting a 55-year-old male patient with unilateral diplopia considering it as a case of multisystem inflammatory syndrome in adults. We also reviewed the literature systematically for the previously reported studies/cases with third, fourth and sixth cranial nerve palsies due to or after Covid-19. RESULTS: The literature search yielded 17 studies reporting 29 patients. 71.4% of the patients were males with a mean age of 42.23 years. Ophthalmological symptoms took 9.7 days to appear after the respiratory involvement. All patients had diplopia as part of their visual symptoms. 41.4% of the patients had unilateral sixth nerve palsy, 24% had bilateral sixth nerve involvement, 17% had fourth nerve involvement, and 27.6% had third nerve involvement. CONCLUSION: Ophthalmoplegia is considered presenting symptom of Covid-19. Further research is needed to detect all neuro-ophthalmological manifestations of Covid-19. |
format | Online Article Text |
id | pubmed-9750665 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-97506652022-12-28 An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review Meshref, Mostafa Shaheen, Nour Swed, Sarya Ibrahim, Mohamed Mostafa, Mostafa Reda Algazar, Mohamed Osman Dobs, Monica Elsayed, Sarah Ibrahim Amro, Yara Afsa, Ahmed Morra, Mostafa Ebraheem Medicine (Baltimore) 5300 Covid-19 has serious sequelae that may be poorly understood, underreported, and, as a result, not diagnosed promptly, such as variations in clinical manifestations of hyperinflammation among people infected with SARS-CoV-2. ophthalmoplegia can be one of these manifestations. METHODS: We are reporting a 55-year-old male patient with unilateral diplopia considering it as a case of multisystem inflammatory syndrome in adults. We also reviewed the literature systematically for the previously reported studies/cases with third, fourth and sixth cranial nerve palsies due to or after Covid-19. RESULTS: The literature search yielded 17 studies reporting 29 patients. 71.4% of the patients were males with a mean age of 42.23 years. Ophthalmological symptoms took 9.7 days to appear after the respiratory involvement. All patients had diplopia as part of their visual symptoms. 41.4% of the patients had unilateral sixth nerve palsy, 24% had bilateral sixth nerve involvement, 17% had fourth nerve involvement, and 27.6% had third nerve involvement. CONCLUSION: Ophthalmoplegia is considered presenting symptom of Covid-19. Further research is needed to detect all neuro-ophthalmological manifestations of Covid-19. Lippincott Williams & Wilkins 2022-12-09 /pmc/articles/PMC9750665/ /pubmed/36626529 http://dx.doi.org/10.1097/MD.0000000000032023 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. |
spellingShingle | 5300 Meshref, Mostafa Shaheen, Nour Swed, Sarya Ibrahim, Mohamed Mostafa, Mostafa Reda Algazar, Mohamed Osman Dobs, Monica Elsayed, Sarah Ibrahim Amro, Yara Afsa, Ahmed Morra, Mostafa Ebraheem An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title | An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title_full | An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title_fullStr | An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title_full_unstemmed | An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title_short | An overview of third, fourth and sixth cranial nerve palsies in the setting of COVID-19: A case report and systematic review |
title_sort | overview of third, fourth and sixth cranial nerve palsies in the setting of covid-19: a case report and systematic review |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750665/ https://www.ncbi.nlm.nih.gov/pubmed/36626529 http://dx.doi.org/10.1097/MD.0000000000032023 |
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