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Pain management of newly diagnosed sarcoma patients at a single center

Systematic pain management of children is insufficient in China, and there is no literature on pain in children with sarcoma. METHODS: Clinical data of 188 patients with newly diagnosed sarcoma admitted to the Medical Oncology Department of Beijing Children’s Hospital was collected from October 2018...

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Autores principales: Yang, Peiyi, Su, Yan, Zhao, Wen, Duan, Chao, Li, Ying, Zhou, Yuchen, Wang, Li, Cai, Siyu, Zhou, Xuan, Ni, Xin, Ma, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750675/
https://www.ncbi.nlm.nih.gov/pubmed/36626440
http://dx.doi.org/10.1097/MD.0000000000031422
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author Yang, Peiyi
Su, Yan
Zhao, Wen
Duan, Chao
Li, Ying
Zhou, Yuchen
Wang, Li
Cai, Siyu
Zhou, Xuan
Ni, Xin
Ma, Xiaoli
author_facet Yang, Peiyi
Su, Yan
Zhao, Wen
Duan, Chao
Li, Ying
Zhou, Yuchen
Wang, Li
Cai, Siyu
Zhou, Xuan
Ni, Xin
Ma, Xiaoli
author_sort Yang, Peiyi
collection PubMed
description Systematic pain management of children is insufficient in China, and there is no literature on pain in children with sarcoma. METHODS: Clinical data of 188 patients with newly diagnosed sarcoma admitted to the Medical Oncology Department of Beijing Children’s Hospital was collected from October 2018 to December 2020. Children experiencing pain received analgesic treatment and regular assessment. RESULTS: Thirty-seven patients (19.7%) suffered from pain. Six cases (16.2%) had mild pain, 17 (46.0%) moderate, and 14 (37.8%) severe. Daily lives of 31 patients were affected by pain. Twenty-six cases had bone invasion. The analgesic rate was 54.1% before admission and 89.2% after admission. Nine cases were treated with oral morphine regularly, and their pain was relieved before chemotherapy; the dose of morphine was 0.14 ± 0.034 mg/kgQ4H when the target was reached. No serious adverse reactions were observed. The period of morphine application after chemotherapy was 5 to 9 days, and there was no withdrawal reaction. CONCLUSION: Pain in children with newly diagnosed sarcoma was mainly moderate to severe, and the incidence of pain in sarcoma with bone invasion was higher, with greater intensity. Patients who received standardized pain assessment and regular analgesics reached pain relief quickly, and no serious adverse reactions were observed within the recommended dosage.
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spelling pubmed-97506752022-12-28 Pain management of newly diagnosed sarcoma patients at a single center Yang, Peiyi Su, Yan Zhao, Wen Duan, Chao Li, Ying Zhou, Yuchen Wang, Li Cai, Siyu Zhou, Xuan Ni, Xin Ma, Xiaoli Medicine (Baltimore) 6100 Systematic pain management of children is insufficient in China, and there is no literature on pain in children with sarcoma. METHODS: Clinical data of 188 patients with newly diagnosed sarcoma admitted to the Medical Oncology Department of Beijing Children’s Hospital was collected from October 2018 to December 2020. Children experiencing pain received analgesic treatment and regular assessment. RESULTS: Thirty-seven patients (19.7%) suffered from pain. Six cases (16.2%) had mild pain, 17 (46.0%) moderate, and 14 (37.8%) severe. Daily lives of 31 patients were affected by pain. Twenty-six cases had bone invasion. The analgesic rate was 54.1% before admission and 89.2% after admission. Nine cases were treated with oral morphine regularly, and their pain was relieved before chemotherapy; the dose of morphine was 0.14 ± 0.034 mg/kgQ4H when the target was reached. No serious adverse reactions were observed. The period of morphine application after chemotherapy was 5 to 9 days, and there was no withdrawal reaction. CONCLUSION: Pain in children with newly diagnosed sarcoma was mainly moderate to severe, and the incidence of pain in sarcoma with bone invasion was higher, with greater intensity. Patients who received standardized pain assessment and regular analgesics reached pain relief quickly, and no serious adverse reactions were observed within the recommended dosage. Lippincott Williams & Wilkins 2022-12-09 /pmc/articles/PMC9750675/ /pubmed/36626440 http://dx.doi.org/10.1097/MD.0000000000031422 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 6100
Yang, Peiyi
Su, Yan
Zhao, Wen
Duan, Chao
Li, Ying
Zhou, Yuchen
Wang, Li
Cai, Siyu
Zhou, Xuan
Ni, Xin
Ma, Xiaoli
Pain management of newly diagnosed sarcoma patients at a single center
title Pain management of newly diagnosed sarcoma patients at a single center
title_full Pain management of newly diagnosed sarcoma patients at a single center
title_fullStr Pain management of newly diagnosed sarcoma patients at a single center
title_full_unstemmed Pain management of newly diagnosed sarcoma patients at a single center
title_short Pain management of newly diagnosed sarcoma patients at a single center
title_sort pain management of newly diagnosed sarcoma patients at a single center
topic 6100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750675/
https://www.ncbi.nlm.nih.gov/pubmed/36626440
http://dx.doi.org/10.1097/MD.0000000000031422
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