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Targeting the androgen receptor to enhance NK cell killing efficacy in bladder cancer by modulating ADAR2/circ_0001005/PD-L1 signaling

Although androgen receptor (AR) can influence bladder cancer (BCa) initiation and progression, its impact on tumor immune escape remains unclear. Here, we found that targeting AR could enhance natural killer (NK) cell tumor-killing efficacy by decreasing PD-L1 expression. Both antiandrogen treatment...

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Detalles Bibliográficos
Autores principales:	Liu, Qing, You, Bosen, Meng, Jialin, Huang, Chi-Ping, Dong, Guanglu, Wang, Ronghao, Chou, Fuju, Gao, Shan, Chang, Chawnshang, Yeh, Shuyuan, Xu, Wanhai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750871/ https://www.ncbi.nlm.nih.gov/pubmed/35915245 http://dx.doi.org/10.1038/s41417-022-00506-w

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