B7-1 mediates podocyte injury and glomerulosclerosis through communication with Hsp90ab1-LRP5-β-catenin pathway

Podocyte injury is a hallmark of glomerular diseases; however, the underlying mechanisms remain unclear. B7-1 is increased in injured podocytes, but its intrinsic role is controversial. The clinical data here revealed the intimate correlation of urinary B7-1 with severity of glomerular injury. Throu...

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Detalles Bibliográficos
Autores principales: Li, Jiemei, Niu, Jing, Min, Wenjian, Ai, Jun, Lin, Xu, Miao, Jinhua, Zhou, Shan, Liang, Ye, Chen, Shuangqin, Ren, Qian, Shen, Kunyu, Wu, Qinyu, Li, Xiaolong, Shen, Weiwei, Hou, Fan Fan, Liu, Youhua, Yang, Peng, Zhou, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750974/
https://www.ncbi.nlm.nih.gov/pubmed/35710882
http://dx.doi.org/10.1038/s41418-022-01026-8

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