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Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro

Major surgery induces systemic inflammation leading to pro-inflammatory activation of endothelial cells. Endothelial inflammation is one of the drivers of postoperative organ damage, including acute kidney injury Tumour Necrosis Factor alpha (TNF-α) is an important component of surgery-induced pro-i...

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Detalles Bibliográficos
Autores principales: Ellermann, Sophie F., Jongman, Rianne M., Luxen, Matthijs, Kuiper, Timara, Plantinga, Josee, Moser, Jill, Scheeren, Thomas W. L., Theilmeier, Gregor, Molema, Grietje, Van Meurs, Matijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750991/
https://www.ncbi.nlm.nih.gov/pubmed/36532777
http://dx.doi.org/10.3389/fphar.2022.992262