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Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro
Major surgery induces systemic inflammation leading to pro-inflammatory activation of endothelial cells. Endothelial inflammation is one of the drivers of postoperative organ damage, including acute kidney injury Tumour Necrosis Factor alpha (TNF-α) is an important component of surgery-induced pro-i...
Autores principales: | Ellermann, Sophie F., Jongman, Rianne M., Luxen, Matthijs, Kuiper, Timara, Plantinga, Josee, Moser, Jill, Scheeren, Thomas W. L., Theilmeier, Gregor, Molema, Grietje, Van Meurs, Matijs |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9750991/ https://www.ncbi.nlm.nih.gov/pubmed/36532777 http://dx.doi.org/10.3389/fphar.2022.992262 |
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