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The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation

Binding of the mitochondrial chaperone TRAP1 to client proteins shapes bioenergetic and proteostatic adaptations of cells, but the panel of TRAP1 clients is only partially defined. Here we show that TRAP1 interacts with F-ATP synthase, the protein complex that provides most cellular ATP. TRAP1 compe...

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Detalles Bibliográficos
Autores principales:	Cannino, Giuseppe, Urbani, Andrea, Gaspari, Marco, Varano, Mariaconcetta, Negro, Alessandro, Filippi, Antonio, Ciscato, Francesco, Masgras, Ionica, Gerle, Christoph, Tibaldi, Elena, Brunati, Anna Maria, Colombo, Giorgio, Lippe, Giovanna, Bernardi, Paolo, Rasola, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751095/ https://www.ncbi.nlm.nih.gov/pubmed/35614131 http://dx.doi.org/10.1038/s41418-022-01020-0

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