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Design, synthesis, in vitro, in silico, and SAR studies of flavone analogs towards anti-dengue activity

Flavone has recently been proved as a promising scaffold for the development of a novel drug against dengue fever, one of the major health threats globally. However, the structure–activity relationship study of flavones on the anti-dengue activity remains mostly limited to the natural-occuring analo...

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Detalles Bibliográficos
Autores principales: Patigo, Apinya, Hengphasatporn, Kowit, Cao, Van, Paunrat, Wattamon, Vijara, Natthanan, Chokmahasarn, Thamonwan, Maitarad, Phornphimon, Rungrotmongkol, Thanyada, Shigeta, Yasuteru, Boonyasuppayakorn, Siwaporn, Khotavivattana, Tanatorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751290/
https://www.ncbi.nlm.nih.gov/pubmed/36517573
http://dx.doi.org/10.1038/s41598-022-25836-5