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Structural investigation of human cystine/glutamate antiporter system x(c) (−) (Sx(c) (−)) using homology modeling and molecular dynamics

The cystine/glutamate antiporter system x(c) (−) (Sx(c) (−)) belongs to the SLC7 family of plasma membrane transporters. It exports intracellular glutamate along the latter’s concentration gradient as a driving force for cellular uptake of cystine. Once imported, cystine is mainly used for the produ...

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Detalles Bibliográficos
Autores principales:	Hang, Tran Dieu, Hung, Huynh Minh, Beckers, Pauline, Desmet, Nathalie, Lamrani, Mohamed, Massie, Ann, Hermans, Emmanuel, Vanommeslaeghe, Kenno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751330/ https://www.ncbi.nlm.nih.gov/pubmed/36533083 http://dx.doi.org/10.3389/fmolb.2022.1064199

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