Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review

There is a strong link between fecal microbiota and the development of type 1 diabetes. As an emerging therapeutic modality, fecal microbiota transplantation has been shown to be safe and effective in the treatment of many intestinal and extraintestinal diseases. Various studies have found that feca...

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Autores principales: Zhang, Shuo, Deng, Feiying, Chen, Jingxian, Chen, Fengwu, Wu, Zezhen, Li, Liping, Hou, Kaijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751335/
https://www.ncbi.nlm.nih.gov/pubmed/36530444
http://dx.doi.org/10.3389/fcimb.2022.1075201
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author Zhang, Shuo
Deng, Feiying
Chen, Jingxian
Chen, Fengwu
Wu, Zezhen
Li, Liping
Hou, Kaijian
author_facet Zhang, Shuo
Deng, Feiying
Chen, Jingxian
Chen, Fengwu
Wu, Zezhen
Li, Liping
Hou, Kaijian
author_sort Zhang, Shuo
collection PubMed
description There is a strong link between fecal microbiota and the development of type 1 diabetes. As an emerging therapeutic modality, fecal microbiota transplantation has been shown to be safe and effective in the treatment of many intestinal and extraintestinal diseases. Various studies have found that fecal microbiota transplantation can treat diseases by correcting patients’ immune disorders. Besides, many studies have found that fecal microbiota transplantation can improve glycemic control and insulin resistance in diabetic patients. Therefore, this paper reviews the mechanism of action of fecal microbiota transplantation on autoimmune-mediated T1DM and the current research progress, feasibility, and issues that need to be addressed in the future development of fecal microbiota transplantation in the treatment of autoimmune-mediated T1DM.
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spelling pubmed-97513352022-12-16 Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review Zhang, Shuo Deng, Feiying Chen, Jingxian Chen, Fengwu Wu, Zezhen Li, Liping Hou, Kaijian Front Cell Infect Microbiol Cellular and Infection Microbiology There is a strong link between fecal microbiota and the development of type 1 diabetes. As an emerging therapeutic modality, fecal microbiota transplantation has been shown to be safe and effective in the treatment of many intestinal and extraintestinal diseases. Various studies have found that fecal microbiota transplantation can treat diseases by correcting patients’ immune disorders. Besides, many studies have found that fecal microbiota transplantation can improve glycemic control and insulin resistance in diabetic patients. Therefore, this paper reviews the mechanism of action of fecal microbiota transplantation on autoimmune-mediated T1DM and the current research progress, feasibility, and issues that need to be addressed in the future development of fecal microbiota transplantation in the treatment of autoimmune-mediated T1DM. Frontiers Media S.A. 2022-12-01 /pmc/articles/PMC9751335/ /pubmed/36530444 http://dx.doi.org/10.3389/fcimb.2022.1075201 Text en Copyright © 2022 Zhang, Deng, Chen, Chen, Wu, Li and Hou https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cellular and Infection Microbiology
Zhang, Shuo
Deng, Feiying
Chen, Jingxian
Chen, Fengwu
Wu, Zezhen
Li, Liping
Hou, Kaijian
Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title_full Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title_fullStr Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title_full_unstemmed Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title_short Fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: A systematic review
title_sort fecal microbiota transplantation treatment of autoimmune-mediated type 1 diabetes: a systematic review
topic Cellular and Infection Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751335/
https://www.ncbi.nlm.nih.gov/pubmed/36530444
http://dx.doi.org/10.3389/fcimb.2022.1075201
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