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Synthetic lethal gene pairs: Experimental approaches and predictive models

Synthetic lethality (SL) refers to a genetic interaction in which the simultaneous perturbation of two genes leads to cell or organism death, whereas viability is maintained when only one of the pair is altered. The experimental exploration of these pairs and predictive modeling in computational bio...

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Detalles Bibliográficos
Autores principales:	Tang, Shan, Gökbağ, Birkan, Fan, Kunjie, Shao, Shuai, Huo, Yang, Wu, Xue, Cheng, Lijun, Li, Lang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751344/ https://www.ncbi.nlm.nih.gov/pubmed/36531238 http://dx.doi.org/10.3389/fgene.2022.961611

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