Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex

The translation initiation complex 4F (eIF4F) is a rate-limiting factor in protein synthesis. Alterations in eIF4F activity are linked to several diseases, including cancer and infectious diseases. To this end, coronaviruses require eIF4F complex activity to produce proteins essential for their life...

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Detalles Bibliográficos
Autores principales: Feng, Yongmei, Grotegut, Stefan, Jovanovic, Predrag, Gandin, Valentina, Olson, Steven H., Murad, Rabi, Beall, Anne, Colayco, Sharon, De-Jesus, Paul, Chanda, Sumit, English, Brian P., Singer, Robert H., Jackson, Michael, Topisirovic, Ivan, Ronai, Ze’ev A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751428/
https://www.ncbi.nlm.nih.gov/pubmed/36532738
http://dx.doi.org/10.3389/fphar.2022.1029093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9751428/
https://www.ncbi.nlm.nih.gov/pubmed/36532738
http://dx.doi.org/10.3389/fphar.2022.1029093

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